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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK3
All Species:
15.76
Human Site:
S666
Identified Species:
31.52
UniProt:
P27448
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27448
NP_001122390.1
776
87005
S666
E
G
S
S
R
N
V
S
A
E
Q
K
D
E
N
Chimpanzee
Pan troglodytes
XP_510184
737
82858
S627
E
G
S
S
R
N
V
S
A
E
Q
K
D
E
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868647
777
86967
S667
E
G
S
S
R
N
V
S
A
E
Q
K
D
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q03141
753
84371
S643
E
G
S
S
R
N
V
S
S
E
Q
K
D
E
N
Rat
Rattus norvegicus
Q8VHF0
797
88733
A643
S
P
S
L
S
H
E
A
T
P
L
S
Q
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
E635
D
Q
K
D
E
N
K
E
A
K
P
R
S
L
R
Chicken
Gallus gallus
Q9IA88
798
88848
S677
Q
P
A
C
P
Q
T
S
Q
T
S
A
T
N
G
Frog
Xenopus laevis
NP_001084256
725
81522
T639
F
T
W
S
M
K
T
T
S
S
M
D
P
N
D
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G878
E
G
Y
G
L
S
Y
G
G
P
S
A
L
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
A1082
A
P
G
A
G
Q
V
A
P
S
L
P
I
H
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
K451
K
I
G
H
Y
N
M
K
C
R
W
V
P
N
S
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
R547
D
L
W
T
I
K
L
R
W
K
Y
D
I
G
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.4
N.A.
94
89.9
N.A.
90.5
31.4
85.6
26.5
N.A.
N.A.
N.A.
39.8
N.A.
Protein Similarity:
100
94.7
N.A.
97.4
N.A.
95
91.2
N.A.
92.9
50.7
89.5
42.6
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
6.6
N.A.
13.3
6.6
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
33.3
20
26.6
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
17
34
0
0
17
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
17
0
0
9
0
0
0
0
0
0
0
17
34
0
9
% D
% Glu:
42
0
0
0
9
0
9
9
0
34
0
0
0
34
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
42
17
9
9
0
0
9
9
0
0
0
0
9
9
% G
% His:
0
0
0
9
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
9
0
0
9
0
0
0
0
0
0
0
17
0
0
% I
% Lys:
9
0
9
0
0
17
9
9
0
17
0
34
0
0
0
% K
% Leu:
0
9
0
9
9
0
9
0
0
0
17
0
9
9
0
% L
% Met:
0
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
50
0
0
0
0
0
0
0
25
42
% N
% Pro:
0
25
0
0
9
0
0
0
9
17
9
9
17
0
0
% P
% Gln:
9
9
0
0
0
17
0
0
9
0
34
0
9
9
9
% Q
% Arg:
0
0
0
0
34
0
0
9
0
9
0
9
0
0
17
% R
% Ser:
9
0
42
42
9
9
0
42
17
17
17
9
9
0
9
% S
% Thr:
0
9
0
9
0
0
17
9
9
9
0
0
9
9
0
% T
% Val:
0
0
0
0
0
0
42
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
17
0
0
0
0
0
9
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
9
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _