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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK3
All Species:
31.82
Human Site:
S273
Identified Species:
63.64
UniProt:
P27448
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27448
NP_001122390.1
776
87005
S273
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Chimpanzee
Pan troglodytes
XP_510184
737
82858
S250
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_868647
777
86967
S274
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q03141
753
84371
S250
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Rat
Rattus norvegicus
Q8VHF0
797
88733
S250
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
S242
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Chicken
Gallus gallus
Q9IA88
798
88848
N297
S
F
S
M
Q
N
Y
N
S
N
L
G
D
Y
N
Frog
Xenopus laevis
NP_001084256
725
81522
S250
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
A253
L
Y
V
L
V
C
G
A
L
P
F
D
G
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S364
L
Y
T
L
V
S
G
S
L
P
F
D
G
Q
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
E82
R
R
K
I
K
N
M
E
M
E
E
K
V
R
R
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L178
H
K
I
V
H
R
D
L
K
P
E
N
L
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.4
N.A.
94
89.9
N.A.
90.5
31.4
85.6
26.5
N.A.
N.A.
N.A.
39.8
N.A.
Protein Similarity:
100
94.7
N.A.
97.4
N.A.
95
91.2
N.A.
92.9
50.7
89.5
42.6
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
6.6
100
66.6
N.A.
N.A.
N.A.
100
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
40
100
73.3
N.A.
N.A.
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
75
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
9
17
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
75
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
75
0
0
0
0
9
75
0
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
9
0
0
0
9
0
0
9
0
0
0
% K
% Leu:
75
0
0
75
0
0
0
9
75
0
9
0
9
9
9
% L
% Met:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
9
0
9
0
9
0
0
75
% N
% Pro:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
67
0
% Q
% Arg:
9
9
0
0
0
9
0
0
0
0
0
0
0
9
9
% R
% Ser:
9
0
9
0
0
67
0
67
9
0
0
0
0
9
0
% S
% Thr:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
0
9
9
75
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
75
0
0
0
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _