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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
15.15
Human Site:
Y91
Identified Species:
30.3
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
Y91
K
K
K
K
V
R
K
Y
W
D
V
P
P
P
G
Chimpanzee
Pan troglodytes
XP_530073
713
78555
S208
G
Q
G
R
R
R
R
S
E
Q
V
R
V
F
S
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
Y87
K
K
K
K
V
R
K
Y
W
D
V
P
P
P
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
Y91
K
K
K
K
V
R
K
Y
W
D
V
P
P
P
G
Rat
Rattus norvegicus
Q63285
419
46487
E70
G
A
A
A
S
A
A
E
Y
G
F
R
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
P89
P
G
F
E
H
I
T
P
L
Q
Y
K
A
M
Q
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
Y94
K
K
K
K
I
K
K
Y
W
D
V
P
P
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
Q67
K
A
M
Q
A
S
G
Q
I
P
A
S
V
V
P
Honey Bee
Apis mellifera
XP_623055
432
48801
I80
P
P
P
G
F
E
H
I
T
P
L
Q
Y
K
A
Nematode Worm
Caenorhab. elegans
P90978
496
55412
E126
A
R
S
R
R
E
P
E
P
Q
K
P
R
E
P
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
P83
P
N
K
Y
W
D
V
P
P
A
G
F
E
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
D197
G
F
D
M
A
P
P
D
M
L
A
A
T
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
0
N.A.
N.A.
N.A.
0
86.6
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
33.3
100
N.A.
N.A.
100
6.6
N.A.
N.A.
N.A.
6.6
100
N.A.
13.3
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
9
17
9
9
0
0
9
17
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
9
0
34
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
17
0
17
9
0
0
0
9
17
0
% E
% Phe:
0
9
9
0
9
0
0
0
0
0
9
9
0
9
0
% F
% Gly:
25
9
9
9
0
0
9
0
0
9
9
0
0
0
34
% G
% His:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
9
9
0
9
9
0
0
0
0
0
0
% I
% Lys:
42
34
42
34
0
9
34
0
0
0
9
9
9
9
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% L
% Met:
0
0
9
9
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
9
9
0
0
9
17
17
17
17
0
42
34
34
17
% P
% Gln:
0
9
0
9
0
0
0
9
0
25
0
9
0
0
9
% Q
% Arg:
0
9
0
17
17
34
9
0
0
0
0
17
9
0
9
% R
% Ser:
0
0
9
0
9
9
0
9
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
0
9
0
0
0
9
0
0
% T
% Val:
0
0
0
0
25
0
9
0
0
0
42
0
17
9
17
% V
% Trp:
0
0
0
0
9
0
0
0
34
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
34
9
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _