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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP5A1
All Species:
53.33
Human Site:
Y246
Identified Species:
90.26
UniProt:
P25705
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25705
NP_001001937.1
553
59751
Y246
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089681
584
62883
Y277
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q03265
553
59734
Y246
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Rat
Rattus norvegicus
P15999
553
59735
Y246
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506958
616
66662
Y309
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Chicken
Gallus gallus
NP_989617
553
60168
Y246
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Frog
Xenopus laevis
P08428
545
58964
D238
K
R
F
N
D
G
T
D
E
K
K
K
L
Y
C
Zebra Danio
Brachydanio rerio
NP_001070823
551
59725
Y245
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35381
552
59403
Y245
S
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Honey Bee
Apis mellifera
XP_392639
547
59493
Y240
K
K
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Nematode Worm
Caenorhab. elegans
Q9XXK1
538
57769
Y231
K
K
K
L
F
C
I
Y
V
A
V
G
Q
K
R
Sea Urchin
Strong. purpuratus
NP_999743
551
59589
Y244
K
N
K
L
Y
C
I
Y
V
A
I
G
Q
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07251
545
58589
Y240
S
K
K
L
Y
C
V
Y
V
A
V
G
Q
K
R
Red Bread Mold
Neurospora crassa
P37211
551
59504
Y244
D
K
K
L
Y
C
V
Y
V
A
V
G
Q
K
R
Conservation
Percent
Protein Identity:
100
N.A.
93.6
N.A.
N.A.
97.4
96.7
N.A.
86.8
91.8
90.4
91.1
N.A.
81.7
81.7
79.1
79.2
Protein Similarity:
100
N.A.
94
N.A.
N.A.
98.9
98.5
N.A.
88.6
96
94.2
95.3
N.A.
90.4
89.6
88.7
90.4
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
100
6.6
100
N.A.
93.3
100
86.6
93.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
100
13.3
100
N.A.
93.3
100
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
69.6
67.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
82.4
81.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
80
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
93
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
93
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
79
0
0
0
72
0
0
0
0
% I
% Lys:
79
86
93
0
0
0
0
0
0
8
8
8
0
93
0
% K
% Leu:
0
0
0
93
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
93
% R
% Ser:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
93
0
22
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
86
0
0
93
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _