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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRD2
All Species:
18.18
Human Site:
S490
Identified Species:
57.14
UniProt:
P25440
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25440
NP_001106653.1
801
88061
S490
E
E
S
S
S
E
S
S
S
E
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001167892
785
86765
S490
E
E
S
S
S
E
S
S
S
E
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001115820
787
86976
S490
E
E
S
S
S
E
S
S
S
E
E
E
E
E
E
Dog
Lupus familis
XP_858054
745
81482
G452
E
E
S
S
S
D
S
G
S
S
D
S
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7JJ13
798
88048
S489
E
E
S
S
S
E
S
S
S
E
E
E
E
E
E
Rat
Rattus norvegicus
Q6MGA9
798
88032
S489
E
E
S
S
S
E
S
S
S
E
E
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505872
1284
139915
D1007
E
E
S
S
S
D
S
D
S
S
D
S
E
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FT54
369
42374
F114
Q
H
K
C
A
W
P
F
M
H
P
V
N
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.1
60.6
N.A.
96.3
96.5
N.A.
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
97.3
69.1
N.A.
97.3
97.2
N.A.
47.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
100
100
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
28.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
0
13
0
0
25
0
0
0
0
% D
% Glu:
88
88
0
0
0
63
0
0
0
63
63
63
88
88
100
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% G
% His:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
88
88
88
0
88
63
88
25
0
25
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _