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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS12 All Species: 40.3
Human Site: T24 Identified Species: 59.11
UniProt: P25398 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25398 NP_001007.2 132 14515 T24 A L Q E V L K T A L I H D G L
Chimpanzee Pan troglodytes XP_001155941 354 38448 T246 A L Q E V L K T A L I H D G L
Rhesus Macaque Macaca mulatta XP_001090713 132 14498 T24 A L Q E V L K T A L I H D G L
Dog Lupus familis XP_859373 99 11358 A14 K P R K R R Q A H L C V L A S
Cat Felis silvestris
Mouse Mus musculus P48316 165 18320 K29 A L E E V L S K A R S Q R T I
Rat Rattus norvegicus P63324 132 14506 T24 A L Q E V L K T A L I H D G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506584 210 22849 T102 A L Q E V L K T A L I H D G L
Chicken Gallus gallus P84175 132 14526 T24 A L Q E V L K T A L I H D G L
Frog Xenopus laevis P47840 132 14482 T24 A L Q E V L K T A L I H D G L
Zebra Danio Brachydanio rerio NP_956340 132 14447 T24 A L P E V L K T A L I H D G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P80455 139 15150 K31 A L Q E V L K K S L I A D G L
Honey Bee Apis mellifera XP_624645 141 15255 N31 A L Q E V L K N A L I H D G V
Nematode Worm Caenorhab. elegans P49196 140 15051 A32 A L R A V L R A A H H A D G L
Sea Urchin Strong. purpuratus XP_795427 144 15284 T38 A L Q E V L K T A L I H E G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKZ3 144 15310 K37 A L E L T V R K S R A Y G G V
Baker's Yeast Sacchar. cerevisiae P48589 143 15453 T34 A L K V V L R T A L V H D G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.2 98.4 69.6 N.A. 26 99.2 N.A. 62.8 99.2 97.7 96.9 N.A. 61.1 68 56.4 72.2
Protein Similarity: 100 37.2 99.2 72.7 N.A. 41.8 99.2 N.A. 62.8 99.2 98.4 98.4 N.A. 75.5 78.7 68.5 79.8
P-Site Identity: 100 100 100 6.6 N.A. 40 100 N.A. 100 100 100 93.3 N.A. 80 86.6 53.3 93.3
P-Site Similarity: 100 100 100 26.6 N.A. 53.3 100 N.A. 100 100 100 93.3 N.A. 86.6 93.3 66.6 100
Percent
Protein Identity: N.A. N.A. N.A. 45.8 47.5 N.A.
Protein Similarity: N.A. N.A. N.A. 66.6 65 N.A.
P-Site Identity: N.A. N.A. N.A. 20 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 94 0 0 7 0 0 0 13 82 0 7 13 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 % D
% Glu: 0 0 13 75 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 7 88 0 % G
% His: 0 0 0 0 0 0 0 0 7 7 7 69 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 69 0 0 0 7 % I
% Lys: 7 0 7 7 0 0 69 19 0 0 0 0 0 0 0 % K
% Leu: 0 94 0 7 0 88 0 0 0 82 0 0 7 0 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 63 0 0 0 7 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 13 0 7 7 19 0 0 13 0 0 7 0 0 % R
% Ser: 0 0 0 0 0 0 7 0 13 0 7 0 0 0 7 % S
% Thr: 0 0 0 0 7 0 0 63 0 0 0 0 0 7 0 % T
% Val: 0 0 0 7 88 7 0 0 0 0 7 7 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _