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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3
All Species:
17.27
Human Site:
S740
Identified Species:
27.14
UniProt:
P25205
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25205
NP_002379.2
808
90981
S740
E
S
Q
K
V
E
L
S
E
S
R
L
K
A
F
Chimpanzee
Pan troglodytes
XP_001151750
808
90957
S740
E
S
Q
K
V
E
L
S
E
S
R
L
K
A
F
Rhesus Macaque
Macaca mulatta
XP_001106966
808
90990
S740
E
S
Q
K
V
E
L
S
E
S
R
L
K
A
F
Dog
Lupus familis
XP_538960
916
102667
S848
E
S
Q
K
V
E
L
S
E
S
R
L
K
E
F
Cat
Felis silvestris
Mouse
Mus musculus
P25206
812
91528
K740
Q
E
T
Q
D
S
Q
K
V
E
L
S
E
P
R
Rat
Rattus norvegicus
XP_001070728
813
91641
Q740
S
Q
E
T
Q
E
S
Q
K
V
E
L
S
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
P741
A
T
G
E
A
K
K
P
E
L
A
D
P
R
L
Frog
Xenopus laevis
Q7ZXZ0
806
90528
D740
A
K
P
G
L
S
G
D
R
L
K
A
F
K
S
Zebra Danio
Brachydanio rerio
NP_997732
807
90502
S739
Q
N
G
H
T
E
L
S
E
D
R
F
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511048
819
90900
S734
A
M
L
M
A
S
P
S
S
E
E
Q
S
V
A
Honey Bee
Apis mellifera
XP_625020
811
91329
I738
S
A
L
D
S
D
C
I
I
L
P
E
T
L
T
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
N697
T
A
D
Q
E
A
L
N
R
I
E
V
Q
M
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
R703
D
Q
N
V
S
A
E
R
I
E
A
F
E
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
F713
S
A
A
R
I
E
T
F
E
R
V
F
G
Q
H
Baker's Yeast
Sacchar. cerevisiae
P24279
971
107499
S824
E
D
D
N
D
I
M
S
P
L
P
A
D
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
86
N.A.
92.9
93.3
N.A.
N.A.
81.4
80.1
75.9
N.A.
62.5
62.7
30.8
N.A.
Protein Similarity:
100
99.8
100
87.2
N.A.
96.6
97
N.A.
N.A.
92
90.7
88.1
N.A.
80
78.6
49.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
0
13.3
N.A.
N.A.
6.6
0
46.6
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
26.6
N.A.
N.A.
26.6
13.3
60
N.A.
6.6
13.3
40
N.A.
Percent
Protein Identity:
N.A.
47.6
N.A.
49.3
39.8
N.A.
Protein Similarity:
N.A.
66
N.A.
68.1
54.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
7
0
14
14
0
0
0
0
14
14
0
27
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
14
7
14
7
0
7
0
7
0
7
7
0
0
% D
% Glu:
34
7
7
7
7
47
7
0
47
20
20
7
14
27
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
20
7
0
34
% F
% Gly:
0
0
14
7
0
0
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
7
7
0
7
14
7
0
0
0
0
0
% I
% Lys:
0
7
0
27
0
7
7
7
7
0
7
0
34
7
7
% K
% Leu:
0
0
14
0
7
0
40
0
0
27
7
34
0
7
14
% L
% Met:
0
7
0
7
0
0
7
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
7
7
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
7
7
7
0
14
0
7
7
0
% P
% Gln:
14
14
27
14
7
0
7
7
0
0
0
7
7
7
0
% Q
% Arg:
0
0
0
7
0
0
0
7
14
7
34
0
0
7
7
% R
% Ser:
20
27
0
0
14
20
7
47
7
27
0
7
14
0
14
% S
% Thr:
7
7
7
7
7
0
7
0
0
0
0
0
7
0
7
% T
% Val:
0
0
0
7
27
0
0
0
7
7
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _