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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CXCR2
All Species:
5.15
Human Site:
Y197
Identified Species:
12.59
UniProt:
P25025
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25025
NP_001548.1
360
40759
Y197
S
N
V
S
P
A
C
Y
E
D
M
G
N
N
T
Chimpanzee
Pan troglodytes
Q28807
357
40365
L207
N
T
A
N
W
R
M
L
L
R
I
L
P
Q
S
Rhesus Macaque
Macaca mulatta
Q28519
353
39929
L207
N
T
A
N
W
R
M
L
L
R
I
L
P
Q
S
Dog
Lupus familis
XP_536065
358
40644
D197
S
S
P
V
C
Y
E
D
M
G
T
N
T
T
K
Cat
Felis silvestris
Mouse
Mus musculus
P35343
359
40407
E197
L
S
T
L
V
C
Y
E
D
V
G
N
N
T
S
Rat
Rattus norvegicus
P35407
359
40513
V209
N
T
S
K
W
R
V
V
L
R
I
L
P
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514199
359
40198
Y197
P
N
S
T
P
V
C
Y
E
N
M
G
K
D
T
Chicken
Gallus gallus
NP_001026762
424
46797
Y240
D
R
N
G
T
V
C
Y
E
R
I
G
N
E
N
Frog
Xenopus laevis
Q7ZXJ7
358
40009
N198
D
R
I
Y
P
I
D
N
R
E
T
W
T
V
G
Zebra Danio
Brachydanio rerio
XP_001337093
340
38670
L197
L
R
I
I
R
H
T
L
G
F
F
L
P
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.8
72.7
N.A.
71.1
71.1
N.A.
57.2
41.5
35.5
43.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
96.1
84.4
N.A.
85
87.2
N.A.
76.1
54.9
53.8
64.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
6.6
6.6
N.A.
53.3
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
13.3
N.A.
26.6
20
N.A.
73.3
40
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
10
30
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
10
10
10
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
10
10
30
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
10
10
10
30
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
10
0
10
0
0
0
0
40
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
20
0
0
10
0
0
0
30
30
0
0
40
0
10
0
% L
% Met:
0
0
0
0
0
0
20
0
10
0
20
0
0
0
0
% M
% Asn:
30
20
10
20
0
0
0
10
0
10
0
20
30
10
10
% N
% Pro:
10
0
10
0
30
0
0
0
0
0
0
0
40
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% Q
% Arg:
0
30
0
0
10
30
0
0
10
40
0
0
0
0
0
% R
% Ser:
20
20
20
10
0
0
0
0
0
0
0
0
0
0
30
% S
% Thr:
0
30
10
10
10
0
10
0
0
0
20
0
20
20
40
% T
% Val:
0
0
10
10
10
20
10
10
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
30
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
10
0
10
10
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _