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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRHBP
All Species:
23.33
Human Site:
Y25
Identified Species:
46.67
UniProt:
P24387
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24387
NP_001873.2
322
36144
Y25
A
L
R
G
E
S
R
Y
L
E
L
R
E
A
A
Chimpanzee
Pan troglodytes
XP_517697
260
28822
Rhesus Macaque
Macaca mulatta
XP_001106453
322
36227
Y25
A
L
R
G
E
S
R
Y
L
E
L
R
E
A
A
Dog
Lupus familis
XP_853211
590
64286
Y293
A
L
R
G
E
T
R
Y
L
Q
L
R
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60571
322
36029
Y25
A
L
R
G
E
S
R
Y
L
E
V
Q
E
A
A
Rat
Rattus norvegicus
P24388
322
36102
Y25
A
L
R
G
E
S
R
Y
L
E
V
Q
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513926
335
37640
K28
F
V
E
T
R
K
E
K
I
Q
G
T
E
R
D
Chicken
Gallus gallus
XP_424801
355
39361
E58
V
R
D
A
G
E
D
E
P
F
L
L
L
S
E
Frog
Xenopus laevis
Q91653
321
36276
Y25
V
L
R
G
E
S
R
Y
I
Q
M
R
E
A
A
Zebra Danio
Brachydanio rerio
NP_001003459
321
35983
D27
R
G
H
A
R
F
L
D
M
Q
D
N
E
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097981
353
38133
Y54
V
A
S
E
A
G
D
Y
I
F
K
K
L
N
P
Honey Bee
Apis mellifera
NP_001012633
332
37518
H36
G
N
D
Y
Q
R
Y
H
Q
Q
I
S
G
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
97.8
46.2
N.A.
87.2
84.4
N.A.
37.9
67.6
68.3
62.7
N.A.
26
26.2
N.A.
N.A.
Protein Similarity:
100
80.7
98.7
50.6
N.A.
93.1
90.6
N.A.
52.5
78.8
78.2
78.8
N.A.
41.9
46.3
N.A.
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
86.6
86.6
N.A.
6.6
6.6
73.3
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
26.6
13.3
93.3
26.6
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
9
0
17
9
0
0
0
0
0
0
0
0
50
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
17
9
0
0
9
0
0
9
9
% D
% Glu:
0
0
9
9
50
9
9
9
0
34
0
0
67
0
9
% E
% Phe:
9
0
0
0
0
9
0
0
0
17
0
0
0
0
0
% F
% Gly:
9
9
0
50
9
9
0
0
0
0
9
0
9
0
0
% G
% His:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
25
0
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
9
0
9
0
0
9
9
0
0
0
% K
% Leu:
0
50
0
0
0
0
9
0
42
0
34
9
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
9
0
0
0
9
42
0
17
0
0
0
% Q
% Arg:
9
9
50
0
17
9
50
0
0
0
0
34
0
9
9
% R
% Ser:
0
0
9
0
0
42
0
0
0
0
0
9
0
9
9
% S
% Thr:
0
0
0
9
0
9
0
0
0
0
0
9
0
0
0
% T
% Val:
25
9
0
0
0
0
0
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _