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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM1
All Species:
57.88
Human Site:
Y738
Identified Species:
84.89
UniProt:
P23921
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23921
NP_001024.1
792
90070
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Chimpanzee
Pan troglodytes
XP_001160029
792
90066
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Rhesus Macaque
Macaca mulatta
XP_001113010
792
90110
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Dog
Lupus familis
XP_534027
792
90191
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P07742
792
90201
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Rat
Rattus norvegicus
NP_001013254
792
90275
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505371
792
90170
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Chicken
Gallus gallus
NP_001026008
790
90074
M736
K
Q
G
L
K
T
G
M
Y
Y
L
R
T
K
P
Frog
Xenopus laevis
NP_001084312
797
90815
Y738
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Zebra Danio
Brachydanio rerio
P79732
794
89798
Y738
G
L
K
T
G
M
Y
Y
L
R
T
K
P
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48591
812
91959
Y749
G
L
K
T
G
M
Y
Y
L
R
T
K
P
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03604
788
88951
K735
S
M
H
F
Y
G
W
K
K
G
L
K
T
G
M
Sea Urchin
Strong. purpuratus
XP_780425
797
89848
Y740
G
L
K
T
G
M
Y
Y
L
R
T
R
P
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJ20
816
91797
Y757
G
L
K
T
G
M
Y
Y
L
R
S
R
A
A
A
Baker's Yeast
Sacchar. cerevisiae
P21672
869
97496
Y742
G
L
K
T
G
M
Y
Y
L
R
T
Q
A
A
S
Red Bread Mold
Neurospora crassa
Q9UW15
929
103785
Y739
G
L
K
T
G
M
Y
Y
L
R
T
Q
A
A
A
Conservation
Percent
Protein Identity:
100
99.8
99.3
97.9
N.A.
97.3
97.4
N.A.
96.2
94
89
89.1
N.A.
73.7
N.A.
73.6
78.9
Protein Similarity:
100
100
99.6
99.3
N.A.
98.6
98.9
N.A.
98.9
97.7
95.7
94.2
N.A.
84.3
N.A.
85.8
88.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
100
86.6
N.A.
93.3
N.A.
0
100
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
100
93.3
N.A.
100
N.A.
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
67.8
60.6
62.5
Protein Similarity:
N.A.
N.A.
N.A.
80.3
77.2
73.4
P-Site Identity:
N.A.
N.A.
N.A.
86.6
80
86.6
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
93.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
19
82
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
88
0
7
0
88
7
7
0
0
7
0
0
0
13
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
88
0
7
0
0
7
7
0
0
19
0
7
0
% K
% Leu:
0
88
0
7
0
0
0
0
88
0
13
0
0
0
0
% L
% Met:
0
7
0
0
0
88
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
69
0
7
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
88
0
69
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% S
% Thr:
0
0
0
88
0
7
0
0
0
0
82
0
13
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
88
88
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _