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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM1
All Species:
46.67
Human Site:
Y104
Identified Species:
68.44
UniProt:
P23921
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23921
NP_001024.1
792
90070
Y104
V
M
E
D
L
Y
N
Y
I
N
P
H
N
G
K
Chimpanzee
Pan troglodytes
XP_001160029
792
90066
Y104
V
M
E
D
L
Y
N
Y
I
N
P
H
N
G
K
Rhesus Macaque
Macaca mulatta
XP_001113010
792
90110
Y104
V
M
E
D
L
Y
N
Y
I
N
P
H
N
G
K
Dog
Lupus familis
XP_534027
792
90191
Y104
V
M
E
D
L
Y
N
Y
I
N
P
H
N
G
R
Cat
Felis silvestris
Mouse
Mus musculus
P07742
792
90201
Y104
V
M
E
D
L
Y
N
Y
I
N
P
H
N
G
R
Rat
Rattus norvegicus
NP_001013254
792
90275
Y104
V
M
E
D
L
Y
N
Y
I
N
P
H
N
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505371
792
90170
Y104
V
M
E
D
L
Y
N
Y
V
N
P
H
N
G
K
Chicken
Gallus gallus
NP_001026008
790
90074
Y104
V
M
D
D
L
Y
N
Y
I
N
P
H
N
G
K
Frog
Xenopus laevis
NP_001084312
797
90815
Y104
V
M
E
D
L
Y
N
Y
V
N
P
L
N
S
K
Zebra Danio
Brachydanio rerio
P79732
794
89798
Y104
V
M
E
D
L
Y
N
Y
V
N
P
L
N
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48591
812
91959
H115
V
F
E
D
L
Y
N
H
V
N
K
E
T
N
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03604
788
88951
F110
V
M
K
T
L
H
E
F
H
H
P
H
T
G
K
Sea Urchin
Strong. purpuratus
XP_780425
797
89848
Y107
V
M
K
D
L
F
E
Y
T
N
P
R
N
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJ20
816
91797
H104
T
I
K
D
M
F
Y
H
V
N
D
R
S
G
L
Baker's Yeast
Sacchar. cerevisiae
P21672
869
97496
W104
V
I
E
D
L
H
D
W
I
N
P
A
T
G
K
Red Bread Mold
Neurospora crassa
Q9UW15
929
103785
Y104
V
I
S
E
L
Y
N
Y
V
N
P
R
T
G
K
Conservation
Percent
Protein Identity:
100
99.8
99.3
97.9
N.A.
97.3
97.4
N.A.
96.2
94
89
89.1
N.A.
73.7
N.A.
73.6
78.9
Protein Similarity:
100
100
99.6
99.3
N.A.
98.6
98.9
N.A.
98.9
97.7
95.7
94.2
N.A.
84.3
N.A.
85.8
88.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
80
73.3
N.A.
46.6
N.A.
46.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
86.6
N.A.
66.6
N.A.
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
67.8
60.6
62.5
Protein Similarity:
N.A.
N.A.
N.A.
80.3
77.2
73.4
P-Site Identity:
N.A.
N.A.
N.A.
20
60
60
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
88
0
0
7
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
69
7
0
0
13
0
0
0
0
7
0
0
0
% E
% Phe:
0
7
0
0
0
13
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
82
0
% G
% His:
0
0
0
0
0
13
0
13
7
7
0
57
0
0
0
% H
% Ile:
0
19
0
0
0
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
0
19
0
0
0
0
0
0
0
7
0
0
0
57
% K
% Leu:
0
0
0
0
94
0
0
0
0
0
0
13
0
0
13
% L
% Met:
0
75
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
75
0
0
94
0
0
69
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
88
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
25
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
0
0
7
13
0
% S
% Thr:
7
0
0
7
0
0
0
0
7
0
0
0
25
0
0
% T
% Val:
94
0
0
0
0
0
0
0
38
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
75
7
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _