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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM1
All Species:
53.94
Human Site:
T751
Identified Species:
79.11
UniProt:
P23921
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23921
NP_001024.1
792
90070
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Chimpanzee
Pan troglodytes
XP_001160029
792
90066
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Rhesus Macaque
Macaca mulatta
XP_001113010
792
90110
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Dog
Lupus familis
XP_534027
792
90191
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P07742
792
90201
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Rat
Rattus norvegicus
NP_001013254
792
90275
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505371
792
90170
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Chicken
Gallus gallus
NP_001026008
790
90074
Q749
K
P
A
A
N
P
I
Q
F
T
L
N
K
E
K
Frog
Xenopus laevis
NP_001084312
797
90815
T751
A
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Zebra Danio
Brachydanio rerio
P79732
794
89798
T751
G
A
N
P
I
Q
F
T
L
N
K
E
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48591
812
91959
T762
A
A
N
A
I
Q
F
T
V
N
K
K
Q
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03604
788
88951
K748
G
M
Y
Y
L
R
T
K
P
A
V
N
A
V
Q
Sea Urchin
Strong. purpuratus
XP_780425
797
89848
T753
A
A
D
P
I
K
F
T
L
D
K
L
S
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJ20
816
91797
T770
A
A
D
A
I
K
F
T
V
D
T
A
M
L
K
Baker's Yeast
Sacchar. cerevisiae
P21672
869
97496
T755
A
S
A
A
I
Q
F
T
I
D
Q
E
V
A
D
Red Bread Mold
Neurospora crassa
Q9UW15
929
103785
T752
A
A
Q
P
I
Q
F
T
V
D
Q
E
A
L
R
Conservation
Percent
Protein Identity:
100
99.8
99.3
97.9
N.A.
97.3
97.4
N.A.
96.2
94
89
89.1
N.A.
73.7
N.A.
73.6
78.9
Protein Similarity:
100
100
99.6
99.3
N.A.
98.6
98.9
N.A.
98.9
97.7
95.7
94.2
N.A.
84.3
N.A.
85.8
88.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
100
93.3
N.A.
60
N.A.
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
100
93.3
N.A.
80
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
67.8
60.6
62.5
Protein Similarity:
N.A.
N.A.
N.A.
80.3
77.2
73.4
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
60
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
66.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
82
82
13
25
0
0
0
0
0
7
0
7
13
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
25
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
69
0
7
0
% E
% Phe:
0
0
0
0
0
0
88
0
7
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
88
0
7
0
7
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
0
13
0
7
0
0
69
7
63
0
75
% K
% Leu:
0
0
0
0
7
0
0
0
63
0
7
7
0
75
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
63
0
7
0
0
0
0
63
0
13
0
0
0
% N
% Pro:
0
7
0
69
0
7
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
75
0
7
0
0
13
0
7
0
7
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
7
88
0
7
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
19
0
7
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _