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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRM1
All Species:
33.33
Human Site:
S780
Identified Species:
48.89
UniProt:
P23921
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23921
NP_001024.1
792
90070
S780
N
T
A
A
M
V
C
S
L
E
N
R
D
E
C
Chimpanzee
Pan troglodytes
XP_001160029
792
90066
S780
N
T
A
A
M
V
C
S
L
E
N
R
D
E
C
Rhesus Macaque
Macaca mulatta
XP_001113010
792
90110
S780
N
T
A
A
M
V
C
S
L
E
N
R
D
E
C
Dog
Lupus familis
XP_534027
792
90191
S780
N
T
A
A
M
V
C
S
L
E
N
R
E
E
C
Cat
Felis silvestris
Mouse
Mus musculus
P07742
792
90201
S780
N
T
A
A
M
V
C
S
L
E
N
R
E
E
C
Rat
Rattus norvegicus
NP_001013254
792
90275
S780
N
T
A
A
M
V
C
S
L
E
N
R
E
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505371
792
90170
S780
N
T
A
A
M
V
C
S
L
E
N
R
E
E
C
Chicken
Gallus gallus
NP_001026008
790
90074
S778
N
K
A
A
M
V
C
S
L
E
N
R
D
E
C
Frog
Xenopus laevis
NP_001084312
797
90815
A780
E
E
K
E
K
N
K
A
A
M
V
C
S
L
E
Zebra Danio
Brachydanio rerio
P79732
794
89798
V780
E
R
N
K
A
A
M
V
C
S
L
E
N
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48591
812
91959
E791
Q
K
Y
E
E
D
R
E
R
K
M
A
D
M
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03604
788
88951
E777
E
T
P
A
T
V
A
E
S
Q
D
E
G
C
L
Sea Urchin
Strong. purpuratus
XP_780425
797
89848
M782
R
A
K
N
E
A
A
M
M
C
S
L
E
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJ20
816
91797
A799
E
D
N
E
T
K
L
A
Q
M
V
C
S
L
T
Baker's Yeast
Sacchar. cerevisiae
P21672
869
97496
T784
P
V
Y
V
P
K
G
T
K
F
S
E
Q
K
A
Red Bread Mold
Neurospora crassa
Q9UW15
929
103785
T781
K
R
S
P
P
A
G
T
Y
T
S
I
V
L
R
Conservation
Percent
Protein Identity:
100
99.8
99.3
97.9
N.A.
97.3
97.4
N.A.
96.2
94
89
89.1
N.A.
73.7
N.A.
73.6
78.9
Protein Similarity:
100
100
99.6
99.3
N.A.
98.6
98.9
N.A.
98.9
97.7
95.7
94.2
N.A.
84.3
N.A.
85.8
88.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
0
0
N.A.
6.6
N.A.
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
6.6
6.6
N.A.
13.3
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
67.8
60.6
62.5
Protein Similarity:
N.A.
N.A.
N.A.
80.3
77.2
73.4
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
50
57
7
19
13
13
7
0
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
50
0
7
7
0
13
0
7
50
% C
% Asp:
0
7
0
0
0
7
0
0
0
0
7
0
32
0
0
% D
% Glu:
25
7
0
19
13
0
0
13
0
50
0
19
32
50
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
13
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
7
13
13
7
7
13
7
0
7
7
0
0
0
7
7
% K
% Leu:
0
0
0
0
0
0
7
0
50
0
7
7
0
19
7
% L
% Met:
0
0
0
0
50
0
7
7
7
13
7
0
0
7
0
% M
% Asn:
50
0
13
7
0
7
0
0
0
0
50
0
7
7
0
% N
% Pro:
7
0
7
7
13
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
7
0
0
7
0
0
% Q
% Arg:
7
13
0
0
0
0
7
0
7
0
0
50
0
7
7
% R
% Ser:
0
0
7
0
0
0
0
50
7
7
19
0
13
0
0
% S
% Thr:
0
50
0
0
13
0
0
13
0
7
0
0
0
0
7
% T
% Val:
0
7
0
7
0
57
0
7
0
0
13
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _