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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCC
All Species:
17.58
Human Site:
T508
Identified Species:
35.15
UniProt:
P23508
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23508
NP_001078846.1
829
93055
T508
R
A
H
D
C
R
K
T
A
E
N
A
A
K
A
Chimpanzee
Pan troglodytes
XP_517879
1064
118580
T693
R
A
H
D
C
R
K
T
A
E
N
A
A
K
A
Rhesus Macaque
Macaca mulatta
XP_001082972
1014
112870
T693
R
A
H
D
C
R
K
T
A
E
N
A
A
K
A
Dog
Lupus familis
XP_853939
829
92784
T508
C
A
H
D
C
R
K
T
A
E
N
A
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R370
680
74812
K380
E
A
S
R
L
L
V
K
K
E
A
T
M
E
V
Rat
Rattus norvegicus
Q3T1I3
680
74593
K380
E
A
S
R
L
L
V
K
K
E
V
A
M
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507243
1025
115224
T705
H
A
H
D
C
R
K
T
A
E
N
A
A
K
A
Chicken
Gallus gallus
XP_413971
825
92902
A506
A
H
D
C
R
K
M
A
E
N
A
A
K
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921192
502
56563
E202
S
D
L
L
S
L
Y
E
A
R
K
Q
Q
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650457
715
80940
A414
N
A
V
A
L
Q
L
A
L
N
C
S
D
R
A
Honey Bee
Apis mellifera
XP_392073
831
92638
D510
D
R
A
I
E
A
Y
D
V
L
V
A
L
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786141
903
100683
R578
L
K
R
V
H
D
N
R
K
V
S
E
N
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.6
81
97
N.A.
24.8
24.6
N.A.
75.3
95.4
N.A.
20.9
N.A.
22.3
32.4
N.A.
48.7
Protein Similarity:
100
77.9
81.5
98.3
N.A.
42.7
42.9
N.A.
78.2
97.4
N.A.
36
N.A.
43.6
54.1
N.A.
63.9
P-Site Identity:
100
100
100
93.3
N.A.
13.3
20
N.A.
93.3
6.6
N.A.
13.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
93.3
13.3
N.A.
13.3
N.A.
33.3
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
9
9
0
9
0
17
50
0
17
67
42
9
67
% A
% Cys:
9
0
0
9
42
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
9
42
0
9
0
9
0
0
0
0
9
9
0
% D
% Glu:
17
0
0
0
9
0
0
9
9
59
0
9
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
9
42
0
9
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
42
17
25
0
9
0
9
42
0
% K
% Leu:
9
0
9
9
25
25
9
0
9
9
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
17
0
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
17
42
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
9
9
0
0
% Q
% Arg:
25
9
9
17
9
42
0
9
0
9
0
0
0
9
0
% R
% Ser:
9
0
17
0
9
0
0
0
0
0
9
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
42
0
0
0
9
0
0
0
% T
% Val:
0
0
9
9
0
0
17
0
9
9
17
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _