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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBG1
All Species:
52.73
Human Site:
Y443
Identified Species:
77.33
UniProt:
P23258
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23258
NP_001061.2
451
51170
Y443
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Chimpanzee
Pan troglodytes
XP_001162175
464
52570
Y456
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548085
451
51005
Y443
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK3
451
51103
Y443
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Rat
Rattus norvegicus
P83888
451
51082
Y443
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418146
427
48240
Y419
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Frog
Xenopus laevis
P23330
451
51149
Y443
H
A
A
T
R
P
D
Y
I
S
W
G
T
Q
D
Zebra Danio
Brachydanio rerio
NP_957202
451
51078
Y443
S
A
A
T
R
P
D
Y
I
S
W
G
T
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23257
475
53321
Y448
E
A
A
T
R
E
D
Y
M
Q
F
S
V
K
R
Honey Bee
Apis mellifera
XP_394981
453
51413
Y443
Q
A
A
T
R
V
D
Y
L
S
W
N
P
S
K
Nematode Worm
Caenorhab. elegans
P34475
444
49910
Y431
V
Q
D
L
L
D
E
Y
K
A
V
V
Q
K
D
Sea Urchin
Strong. purpuratus
NP_999657
460
51977
Y446
H
A
A
T
K
P
D
Y
I
S
W
G
T
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41808
469
52822
Y446
K
A
C
E
S
P
D
Y
I
K
W
G
M
E
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38558
474
53259
Y446
K
A
C
E
S
P
D
Y
I
K
W
G
M
E
D
Baker's Yeast
Sacchar. cerevisiae
P53378
473
52609
Y445
V
A
A
E
Q
D
S
Y
L
D
D
V
L
V
D
Red Bread Mold
Neurospora crassa
P53377
461
51580
Y443
E
A
A
E
D
A
N
Y
L
N
P
E
L
G
E
Conservation
Percent
Protein Identity:
100
97.1
N.A.
98.2
N.A.
96.9
98.8
N.A.
N.A.
92.2
98.2
98
N.A.
75.3
83.6
43.9
84.1
Protein Similarity:
100
97.1
N.A.
99.7
N.A.
98.2
99.5
N.A.
N.A.
93.3
99.3
99.3
N.A.
85.6
93.3
64.9
93
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
40
53.3
6.6
86.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
60
66.6
33.3
100
Percent
Protein Identity:
N.A.
72
N.A.
72.1
38.9
66.1
Protein Similarity:
N.A.
83.1
N.A.
82.7
59.8
80.6
P-Site Identity:
N.A.
46.6
N.A.
46.6
20
26.6
P-Site Similarity:
N.A.
60
N.A.
60
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
94
82
0
0
7
0
0
0
7
0
0
0
0
0
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
13
82
0
0
7
7
0
0
0
32
% D
% Glu:
13
0
0
25
0
7
7
0
0
0
0
7
0
13
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
69
0
7
0
% G
% His:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
69
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
7
0
0
0
7
13
0
0
0
13
7
% K
% Leu:
0
0
0
7
7
0
0
0
19
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
69
0
0
0
0
7
0
7
0
0
% P
% Gln:
7
7
0
0
7
0
0
0
0
7
0
0
7
57
7
% Q
% Arg:
0
0
0
0
63
0
0
0
0
0
0
0
0
0
7
% R
% Ser:
7
0
0
0
13
0
7
0
0
63
0
7
0
7
0
% S
% Thr:
0
0
0
69
0
0
0
0
0
0
0
0
57
0
0
% T
% Val:
13
0
0
0
0
7
0
0
0
0
7
13
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _