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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBG1
All Species:
41.52
Human Site:
Y395
Identified Species:
60.89
UniProt:
P23258
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23258
NP_001061.2
451
51170
Y395
F
E
R
T
C
R
Q
Y
D
K
L
R
K
R
E
Chimpanzee
Pan troglodytes
XP_001162175
464
52570
Y408
F
E
R
T
C
R
Q
Y
D
K
L
R
K
R
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548085
451
51005
Y395
F
E
S
S
C
Q
Q
Y
D
K
L
R
K
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK3
451
51103
Y395
F
E
S
S
C
Q
Q
Y
D
K
L
W
K
R
G
Rat
Rattus norvegicus
P83888
451
51082
F395
F
E
R
T
C
R
Q
F
D
K
L
R
K
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418146
427
48240
F380
K
L
R
K
R
E
A
F
L
E
Q
F
R
K
E
Frog
Xenopus laevis
P23330
451
51149
Y395
F
E
R
T
C
R
Q
Y
D
K
L
R
K
R
E
Zebra Danio
Brachydanio rerio
NP_957202
451
51078
Y395
F
E
R
T
C
R
Q
Y
D
K
L
R
K
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23257
475
53321
Y400
F
E
R
A
L
N
Q
Y
D
K
L
R
K
R
G
Honey Bee
Apis mellifera
XP_394981
453
51413
Y395
F
D
R
A
L
Q
Q
Y
D
K
L
R
K
R
E
Nematode Worm
Caenorhab. elegans
P34475
444
49910
Y393
F
E
S
L
L
S
K
Y
D
K
L
R
S
K
R
Sea Urchin
Strong. purpuratus
NP_999657
460
51977
F398
F
E
R
T
C
S
Q
F
D
K
L
R
K
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q41808
469
52822
Y397
F
G
K
C
L
G
Q
Y
E
K
L
R
K
K
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38558
474
53259
Y397
F
S
R
C
L
S
Q
Y
D
K
L
R
K
K
Q
Baker's Yeast
Sacchar. cerevisiae
P53378
473
52609
F394
F
E
N
A
C
N
T
F
D
K
V
F
A
K
G
Red Bread Mold
Neurospora crassa
P53377
461
51580
Y395
F
K
R
I
V
R
Q
Y
D
G
M
R
K
R
N
Conservation
Percent
Protein Identity:
100
97.1
N.A.
98.2
N.A.
96.9
98.8
N.A.
N.A.
92.2
98.2
98
N.A.
75.3
83.6
43.9
84.1
Protein Similarity:
100
97.1
N.A.
99.7
N.A.
98.2
99.5
N.A.
N.A.
93.3
99.3
99.3
N.A.
85.6
93.3
64.9
93
P-Site Identity:
100
100
N.A.
80
N.A.
66.6
93.3
N.A.
N.A.
13.3
100
100
N.A.
73.3
73.3
46.6
86.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
80
100
N.A.
N.A.
40
100
100
N.A.
73.3
86.6
60
93.3
Percent
Protein Identity:
N.A.
72
N.A.
72.1
38.9
66.1
Protein Similarity:
N.A.
83.1
N.A.
82.7
59.8
80.6
P-Site Identity:
N.A.
46.6
N.A.
60
33.3
60
P-Site Similarity:
N.A.
73.3
N.A.
73.3
53.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
7
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
13
57
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
88
0
0
0
0
0
0
% D
% Glu:
0
69
0
0
0
7
0
0
7
7
0
0
0
0
57
% E
% Phe:
94
0
0
0
0
0
0
25
0
0
0
13
0
0
0
% F
% Gly:
0
7
0
0
0
7
0
0
0
7
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
7
7
0
0
7
0
0
88
0
0
82
32
0
% K
% Leu:
0
7
0
7
32
0
0
0
7
0
82
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
7
0
0
13
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
19
82
0
0
0
7
0
0
0
13
% Q
% Arg:
0
0
69
0
7
38
0
0
0
0
0
82
7
69
7
% R
% Ser:
0
7
19
13
0
19
0
0
0
0
0
0
7
0
0
% S
% Thr:
0
0
0
38
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _