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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBG1 All Species: 42.42
Human Site: S386 Identified Species: 62.22
UniProt: P23258 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23258 NP_001061.2 451 51170 S386 A N H T S I S S L F E R T C R
Chimpanzee Pan troglodytes XP_001162175 464 52570 S399 A N H T S I S S L F E R T C R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548085 451 51005 S386 A N H T S I S S L F E S S C Q
Cat Felis silvestris
Mouse Mus musculus Q8VCK3 451 51103 S386 A N H T S I S S L F E S S C Q
Rat Rattus norvegicus P83888 451 51082 S386 A N H T S I S S L F E R T C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418146 427 48240 Y371 F E R T C R Q Y D K L R K R E
Frog Xenopus laevis P23330 451 51149 S386 A N H T N I S S L F E R T C R
Zebra Danio Brachydanio rerio NP_957202 451 51078 S386 A N H T S I S S L F E R T C R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23257 475 53321 S391 A N H T S I C S L F E R A L N
Honey Bee Apis mellifera XP_394981 453 51413 S386 A N H T N I S S L F D R A L Q
Nematode Worm Caenorhab. elegans P34475 444 49910 P384 N N S T S V A P L F E S L L S
Sea Urchin Strong. purpuratus NP_999657 460 51977 S389 A N H T S I V S L F E R T C S
Poplar Tree Populus trichocarpa
Maize Zea mays Q41808 469 52822 H388 A N H T S I R H L F G K C L G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38558 474 53259 H388 A S H T S I R H L F S R C L S
Baker's Yeast Sacchar. cerevisiae P53378 473 52609 N385 S N M S T V V N V F E N A C N
Red Bread Mold Neurospora crassa P53377 461 51580 T386 A N H T S I A T L F K R I V R
Conservation
Percent
Protein Identity: 100 97.1 N.A. 98.2 N.A. 96.9 98.8 N.A. N.A. 92.2 98.2 98 N.A. 75.3 83.6 43.9 84.1
Protein Similarity: 100 97.1 N.A. 99.7 N.A. 98.2 99.5 N.A. N.A. 93.3 99.3 99.3 N.A. 85.6 93.3 64.9 93
P-Site Identity: 100 100 N.A. 80 N.A. 80 100 N.A. N.A. 13.3 93.3 100 N.A. 73.3 66.6 40 86.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 100 N.A. N.A. 13.3 100 100 N.A. 73.3 86.6 53.3 86.6
Percent
Protein Identity: N.A. 72 N.A. 72.1 38.9 66.1
Protein Similarity: N.A. 83.1 N.A. 82.7 59.8 80.6
P-Site Identity: N.A. 53.3 N.A. 53.3 26.6 66.6
P-Site Similarity: N.A. 60 N.A. 60 66.6 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 0 0 0 0 0 13 0 0 0 0 0 19 0 0 % A
% Cys: 0 0 0 0 7 0 7 0 0 0 0 0 13 57 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 69 0 0 0 7 % E
% Phe: 7 0 0 0 0 0 0 0 0 94 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 7 % G
% His: 0 0 82 0 0 0 0 13 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 82 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 7 7 7 7 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 88 0 7 0 7 32 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 88 0 0 13 0 0 7 0 0 0 7 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 19 % Q
% Arg: 0 0 7 0 0 7 13 0 0 0 0 69 0 7 38 % R
% Ser: 7 7 7 7 75 0 50 63 0 0 7 19 13 0 19 % S
% Thr: 0 0 0 94 7 0 0 7 0 0 0 0 38 0 0 % T
% Val: 0 0 0 0 0 13 13 0 7 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _