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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGS1
All Species:
25.15
Human Site:
Y63
Identified Species:
61.48
UniProt:
P23219
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23219
NP_000953.2
599
68656
Y63
C
D
C
T
R
T
G
Y
S
G
P
N
C
T
I
Chimpanzee
Pan troglodytes
XP_520238
574
66115
L52
I
P
G
L
W
T
W
L
R
N
S
L
R
P
S
Rhesus Macaque
Macaca mulatta
XP_001088270
599
68565
Y63
C
D
C
T
R
T
G
Y
S
G
P
N
C
T
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P22437
602
69024
Y66
C
D
C
T
R
T
G
Y
S
G
P
N
C
T
I
Rat
Rattus norvegicus
Q63921
602
69014
Y66
C
D
C
T
R
T
G
Y
S
G
P
N
C
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512281
641
72069
Y105
C
D
C
T
R
T
G
Y
H
G
R
N
C
T
S
Chicken
Gallus gallus
P27607
603
69094
F59
E
N
C
T
T
P
E
F
F
T
W
L
K
L
I
Frog
Xenopus laevis
NP_001091389
587
67774
Y56
C
D
C
T
R
T
G
Y
Y
G
T
N
C
T
I
Zebra Danio
Brachydanio rerio
NP_705942
597
68945
Y64
C
D
C
T
R
T
G
Y
Y
G
E
N
C
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEG6
809
90521
C94
S
H
E
K
P
Q
I
C
D
L
P
A
G
K
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
98.3
N.A.
N.A.
89.1
87.5
N.A.
71.4
63.1
70.9
67.4
N.A.
21.6
N.A.
N.A.
N.A.
Protein Similarity:
100
95.6
99.3
N.A.
N.A.
93.8
93
N.A.
80.8
78.2
83.3
80.1
N.A.
36.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
N.A.
N.A.
100
100
N.A.
80
20
86.6
86.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
N.A.
N.A.
100
100
N.A.
80
33.3
86.6
86.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
70
0
80
0
0
0
0
10
0
0
0
0
70
0
0
% C
% Asp:
0
70
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
70
0
0
70
0
0
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
70
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
0
0
0
10
0
0
0
10
0
10
0
20
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
70
0
0
0
% N
% Pro:
0
10
0
0
10
10
0
0
0
0
50
0
0
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
10
0
10
0
10
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
40
0
10
0
0
0
20
% S
% Thr:
0
0
0
80
10
80
0
0
0
10
10
0
0
70
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _