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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRC1
All Species:
13.03
Human Site:
Y850
Identified Species:
57.33
UniProt:
P22897
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22897
NP_002429.1
1456
166012
Y850
E
K
K
F
L
W
K
Y
V
N
R
N
D
A
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001091661
1456
165929
Y850
E
K
K
F
L
W
K
Y
V
N
R
N
D
A
Q
Dog
Lupus familis
XP_544242
1462
166424
Y857
K
K
K
F
L
W
K
Y
V
N
R
N
D
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61830
1456
165048
Y850
E
K
K
F
L
W
K
Y
I
N
K
N
G
G
Q
Rat
Rattus norvegicus
Q4TU93
1480
167004
K877
F
L
G
Q
N
M
Q
K
L
S
S
D
Q
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687939
1411
161313
W817
E
E
E
R
L
F
L
W
H
K
S
K
E
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98
88.3
N.A.
81.9
34.8
N.A.
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.1
93.7
N.A.
90.4
53.6
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
73.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
33.3
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
17
50
0
0
% D
% Glu:
67
17
17
0
0
0
0
0
0
0
0
0
17
17
0
% E
% Phe:
17
0
0
67
0
17
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
0
0
0
0
0
17
17
0
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% I
% Lys:
17
67
67
0
0
0
67
17
0
17
17
17
0
0
0
% K
% Leu:
0
17
0
0
84
0
17
0
17
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
67
0
67
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
17
0
0
0
0
0
17
0
84
% Q
% Arg:
0
0
0
17
0
0
0
0
0
0
50
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
17
34
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
67
0
17
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _