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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRC1 All Species: 14.24
Human Site: T820 Identified Species: 62.67
UniProt: P22897 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22897 NP_002429.1 1456 166012 T820 Y F S K E K E T M D N A R A F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091661 1456 165929 T820 Y F S K E K E T M D N A R A F
Dog Lupus familis XP_544242 1462 166424 T827 Y F S K E K E T M D K A R E F
Cat Felis silvestris
Mouse Mus musculus Q61830 1456 165048 T820 Y F S K E K E T M D N A R R F
Rat Rattus norvegicus Q4TU93 1480 167004 S844 K F F E H H S S W A Q A Q R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687939 1411 161313 M788 Y G S E Y S A M S M H E A R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98 88.3 N.A. 81.9 34.8 N.A. N.A. N.A. N.A. 40.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99.1 93.7 N.A. 90.4 53.6 N.A. N.A. N.A. N.A. 56.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 13.3 N.A. N.A. N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 86.6 N.A. 93.3 33.3 N.A. N.A. N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 17 0 0 17 0 84 17 34 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % D
% Glu: 0 0 0 34 67 0 67 0 0 0 0 17 0 17 0 % E
% Phe: 0 84 17 0 0 0 0 0 0 0 0 0 0 0 67 % F
% Gly: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 17 17 0 0 0 0 17 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % I
% Lys: 17 0 0 67 0 67 0 0 0 0 17 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 17 67 17 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 17 0 17 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 67 50 0 % R
% Ser: 0 0 84 0 0 17 17 17 17 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % W
% Tyr: 84 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _