KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP7A1
All Species:
29.39
Human Site:
T80
Identified Species:
64.67
UniProt:
P22680
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22680
NP_000771.2
504
57661
T80
G
K
Y
V
H
F
I
T
N
P
L
S
Y
H
K
Chimpanzee
Pan troglodytes
XP_519773
504
57628
T80
G
K
Y
V
H
F
I
T
N
P
L
S
Y
H
K
Rhesus Macaque
Macaca mulatta
XP_001087135
504
57781
T80
G
K
Y
V
H
F
I
T
N
P
L
S
Y
H
K
Dog
Lupus familis
XP_544091
501
57140
T80
G
N
Y
V
H
F
I
T
N
P
L
S
Y
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64505
503
57240
T80
G
K
Y
V
H
F
I
T
N
S
L
S
Y
H
K
Rat
Rattus norvegicus
P18125
503
56864
T80
G
K
Y
V
H
F
I
T
N
S
L
S
Y
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514400
507
57946
T80
G
K
Y
V
H
F
L
T
N
P
F
S
F
H
T
Chicken
Gallus gallus
NP_001001753
513
59294
T81
G
K
Y
I
H
F
L
T
D
P
F
S
Y
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957467
512
58721
C81
G
Q
Y
V
H
F
L
C
D
P
F
S
Y
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W011
510
58195
G102
S
T
T
L
L
E
K
G
Q
L
Y
E
Y
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5Y2
489
56732
K87
Y
G
R
T
G
I
Y
K
A
H
M
F
G
Y
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.2
84.9
N.A.
81.5
82.3
N.A.
75.1
65.8
N.A.
63.4
N.A.
22.1
N.A.
N.A.
N.A.
Protein Similarity:
100
100
98.6
92.2
N.A.
90.8
90.6
N.A.
88.3
83
N.A.
80.8
N.A.
40.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
73.3
66.6
N.A.
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
82
0
0
0
0
28
10
10
0
0
% F
% Gly:
82
10
0
0
10
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
82
0
0
0
0
10
0
0
0
73
0
% H
% Ile:
0
0
0
10
0
10
55
0
0
0
0
0
0
0
0
% I
% Lys:
0
64
0
0
0
0
10
10
0
0
0
0
0
0
55
% K
% Leu:
0
0
0
10
10
0
28
0
0
10
55
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
64
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
0
0
0
0
0
0
0
0
19
0
82
0
0
10
% S
% Thr:
0
10
10
10
0
0
0
73
0
0
0
0
0
0
10
% T
% Val:
0
0
0
73
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
82
0
0
0
10
0
0
0
10
0
82
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _