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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1T
All Species:
11.21
Human Site:
S127
Identified Species:
24.67
UniProt:
P22492
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22492
NP_005314.2
207
22019
S127
T
R
S
K
A
K
K
S
V
S
A
K
T
K
K
Chimpanzee
Pan troglodytes
XP_527257
209
22156
S127
T
R
S
K
A
K
K
S
V
S
A
K
T
K
K
Rhesus Macaque
Macaca mulatta
P40286
208
22075
S127
T
R
R
K
A
N
K
S
A
S
A
K
T
K
K
Dog
Lupus familis
XP_545388
212
21915
R127
P
A
K
S
R
V
K
R
P
P
S
T
K
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q07133
208
21522
S127
G
K
G
K
K
S
A
S
A
K
A
K
K
M
G
Rat
Rattus norvegicus
P06349
208
21707
S127
G
K
G
K
K
S
A
S
A
K
A
K
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
G136
A
K
P
K
K
S
A
G
A
A
K
K
P
K
K
Chicken
Gallus gallus
P08287
225
22510
A128
E
K
A
P
K
K
K
A
S
A
A
K
P
K
K
Frog
Xenopus laevis
P06892
210
21355
P129
A
A
A
K
K
K
A
P
L
A
A
E
A
K
K
Zebra Danio
Brachydanio rerio
NP_001017660
201
20684
K122
K
K
P
V
V
K
K
K
K
A
A
A
K
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
K132
K
D
P
K
A
K
S
K
V
L
S
A
E
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
88.9
66.9
N.A.
63.4
64.4
N.A.
54.2
48.8
39
45.4
N.A.
33.5
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
91.8
75.4
N.A.
74.5
75.4
N.A.
65.4
61.7
55.7
59.9
N.A.
49.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
13.3
N.A.
26.6
26.6
N.A.
26.6
40
33.3
20
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
20
N.A.
33.3
33.3
N.A.
40
66.6
60
33.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
19
0
37
0
37
10
37
37
73
19
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
19
0
0
0
0
10
0
0
0
0
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
46
10
73
46
55
55
19
10
19
10
64
37
64
73
% K
% Leu:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
28
10
0
0
0
10
10
10
0
0
19
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
28
10
0
10
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
10
0
28
10
46
10
28
19
0
0
0
0
% S
% Thr:
28
0
0
0
0
0
0
0
0
0
0
10
28
10
0
% T
% Val:
0
0
0
10
10
10
0
0
28
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _