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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNA4 All Species: 28.48
Human Site: S561 Identified Species: 62.67
UniProt: P22459 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22459 NP_002224.1 653 73288 S561 L P V P V I V S N F N Y F Y H
Chimpanzee Pan troglodytes XP_524797 575 63732 N484 P V I V S N F N Y F Y H R E T
Rhesus Macaque Macaca mulatta XP_001088267 652 73147 S560 L P V P V I V S N F N Y F Y H
Dog Lupus familis XP_542545 666 74147 S574 L P V P V I V S N F N Y F Y H
Cat Felis silvestris
Mouse Mus musculus Q61423 654 73455 S562 L P V P V I V S N F N Y F Y H
Rat Rattus norvegicus P15385 655 73372 S563 L P V P V I V S N F N Y F Y H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505719 2035 215303 S1943 L P V P V I V S N F N Y F Y H
Chicken Gallus gallus Q7T199 516 58965 T425 W W A V V T M T T V G Y G D M
Frog Xenopus laevis P22739 499 56683 V408 T I A L P V P V I V S N F N Y
Zebra Danio Brachydanio rerio XP_687427 641 71769 S547 L P V P V I V S N F N Y F Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08510 655 74175 Q563 G A Q Q Q Q Q Q P V A S S L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.1 97.6 86.6 N.A. 95.5 96.4 N.A. 29.6 51.2 55.1 68.1 N.A. 52.2 N.A. N.A. N.A.
Protein Similarity: 100 68.1 97.6 90.2 N.A. 96.9 97.7 N.A. 30.8 62.6 63.8 79.4 N.A. 67.1 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 13.3 6.6 100 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 100 26.6 26.6 100 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 73 0 0 73 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 64 % H
% Ile: 0 10 10 0 0 64 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 64 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 10 0 10 64 0 64 10 0 10 0 % N
% Pro: 10 64 0 64 10 0 10 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 10 10 10 10 10 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 10 0 0 64 0 0 10 10 10 0 10 % S
% Thr: 10 0 0 0 0 10 0 10 10 0 0 0 0 0 10 % T
% Val: 0 10 64 19 73 10 64 10 0 28 0 0 0 0 0 % V
% Trp: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 10 73 0 64 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _