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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPX3
All Species:
14.85
Human Site:
Y53
Identified Species:
29.7
UniProt:
P22352
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22352
NP_002075.2
226
25552
Y53
L
T
I
D
G
E
E
Y
I
P
F
K
Q
Y
A
Chimpanzee
Pan troglodytes
Q0EFA0
201
21781
R62
T
Q
M
N
E
L
Q
R
R
L
G
P
R
G
L
Rhesus Macaque
Macaca mulatta
NP_001152772
226
25408
Y53
L
T
I
D
G
E
E
Y
I
P
F
K
Q
Y
I
Dog
Lupus familis
XP_855017
147
16748
E32
F
G
K
Q
E
P
G
E
N
S
E
I
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P46412
226
25256
Y53
L
T
I
D
G
E
E
Y
I
P
F
K
Q
Y
A
Rat
Rattus norvegicus
P23764
226
25256
Y53
L
T
I
D
G
E
E
Y
I
P
F
K
Q
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001156704
219
24474
M61
F
R
K
Y
A
G
K
M
V
L
F
V
N
V
A
Frog
Xenopus laevis
NP_001085319
233
26458
F53
T
T
L
D
G
S
Q
F
I
P
F
K
A
Y
Q
Zebra Danio
Brachydanio rerio
NP_001131027
222
24765
H61
F
S
H
Y
A
G
K
H
V
L
V
V
N
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95003
224
25537
Y53
I
E
T
L
Q
G
E
Y
T
D
L
S
Q
Y
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04922
169
18926
L54
N
Y
K
E
L
N
V
L
Y
E
K
Y
K
E
Q
Baker's Yeast
Sacchar. cerevisiae
P38143
162
18388
E47
T
P
Q
Y
K
E
L
E
E
L
Y
K
K
Y
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.8
96
60.6
N.A.
89.3
90.7
N.A.
N.A.
67.2
56.6
57.9
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
100
53.5
98.6
62.8
N.A.
94.2
95.1
N.A.
N.A.
81.8
71.6
68.5
N.A.
N.A.
N.A.
55.3
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
100
100
N.A.
N.A.
13.3
53.3
6.6
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
100
26.6
93.3
6.6
N.A.
100
100
N.A.
N.A.
26.6
73.3
33.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
0
0
0
9
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
42
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
9
0
9
17
42
42
17
9
9
9
0
0
9
0
% E
% Phe:
25
0
0
0
0
0
0
9
0
0
50
0
0
0
0
% F
% Gly:
0
9
0
0
42
25
9
0
0
0
9
0
0
9
0
% G
% His:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
34
0
0
0
0
0
42
0
0
9
0
0
9
% I
% Lys:
0
0
25
0
9
0
17
0
0
0
9
50
17
0
0
% K
% Leu:
34
0
9
9
9
9
9
9
0
34
9
0
9
0
9
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
9
0
0
9
0
0
0
17
0
0
% N
% Pro:
0
9
0
0
0
9
0
0
0
42
0
9
0
9
0
% P
% Gln:
0
9
9
9
9
0
17
0
0
0
0
0
42
0
25
% Q
% Arg:
0
9
0
0
0
0
0
9
9
0
0
0
9
0
9
% R
% Ser:
0
9
0
0
0
9
0
0
0
9
0
9
0
0
9
% S
% Thr:
25
42
9
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
17
0
9
17
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
25
0
0
0
42
9
0
9
9
0
59
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _