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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPX3
All Species:
24.24
Human Site:
Y149
Identified Species:
48.48
UniProt:
P22352
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22352
NP_002075.2
226
25552
Y149
G
E
K
E
Q
K
F
Y
T
F
L
K
N
S
C
Chimpanzee
Pan troglodytes
Q0EFA0
201
21781
P134
L
R
E
A
L
P
A
P
S
D
D
A
T
A
L
Rhesus Macaque
Macaca mulatta
NP_001152772
226
25408
Y149
G
E
K
E
Q
K
F
Y
T
F
L
K
N
S
C
Dog
Lupus familis
XP_855017
147
16748
K96
R
L
F
W
E
P
M
K
V
H
D
I
R
W
N
Cat
Felis silvestris
Mouse
Mus musculus
P46412
226
25256
Y149
G
E
K
E
Q
K
F
Y
T
F
L
K
N
S
C
Rat
Rattus norvegicus
P23764
226
25256
Y149
G
E
K
E
Q
K
F
Y
T
F
L
K
N
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001156704
219
24474
Y147
G
A
K
E
Q
K
V
Y
S
F
L
K
N
S
C
Frog
Xenopus laevis
NP_001085319
233
26458
Y149
G
R
K
E
Q
K
F
Y
T
F
L
K
N
S
C
Zebra Danio
Brachydanio rerio
NP_001131027
222
24765
F147
G
D
G
E
Q
A
L
F
T
F
L
K
N
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q95003
224
25537
Y151
G
D
N
H
H
P
L
Y
E
F
V
K
E
S
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04922
169
18926
A118
P
L
Y
K
Y
L
K
A
E
K
G
G
L
L
I
Baker's Yeast
Sacchar. cerevisiae
P38143
162
18388
L111
A
D
S
V
Y
N
Y
L
K
S
Q
K
A
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.8
96
60.6
N.A.
89.3
90.7
N.A.
N.A.
67.2
56.6
57.9
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
100
53.5
98.6
62.8
N.A.
94.2
95.1
N.A.
N.A.
81.8
71.6
68.5
N.A.
N.A.
N.A.
55.3
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
N.A.
80
93.3
60
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
100
20
100
6.6
N.A.
100
100
N.A.
N.A.
86.6
93.3
80
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
9
9
9
0
0
0
9
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% C
% Asp:
0
25
0
0
0
0
0
0
0
9
17
0
0
0
0
% D
% Glu:
0
34
9
59
9
0
0
0
17
0
0
0
9
0
0
% E
% Phe:
0
0
9
0
0
0
42
9
0
67
0
0
0
0
0
% F
% Gly:
67
0
9
0
0
0
0
0
0
0
9
9
0
9
0
% G
% His:
0
0
0
9
9
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
0
0
50
9
0
50
9
9
9
9
0
75
0
0
0
% K
% Leu:
9
17
0
0
9
9
17
9
0
0
59
0
9
9
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
9
0
0
0
0
0
0
59
0
9
% N
% Pro:
9
0
0
0
0
25
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
59
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
9
17
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
9
0
0
0
0
0
17
9
0
0
0
59
0
% S
% Thr:
0
0
0
0
0
0
0
0
50
0
0
0
9
0
0
% T
% Val:
0
0
0
9
0
0
9
0
9
0
9
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
17
0
9
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _