KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAICS
All Species:
23.64
Human Site:
S219
Identified Species:
43.33
UniProt:
P22234
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22234
NP_001072992.1
425
47079
S219
D
S
W
R
L
W
P
S
G
D
R
S
Q
Q
K
Chimpanzee
Pan troglodytes
XP_001140521
451
49634
S245
D
S
W
R
L
W
P
S
G
D
R
S
Q
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532381
425
46974
S219
D
S
W
R
L
W
P
S
G
D
R
S
Q
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCL9
425
47052
S219
D
S
W
R
L
W
P
S
G
D
R
S
Q
Q
K
Rat
Rattus norvegicus
P51583
425
47078
S219
D
S
W
R
L
W
P
S
G
D
R
S
Q
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516499
348
38076
T166
Y
R
D
L
K
E
V
T
P
E
G
L
Q
M
V
Chicken
Gallus gallus
P38024
426
47222
S220
D
S
W
R
L
W
P
S
G
D
R
S
Q
Q
K
Frog
Xenopus laevis
NP_001080163
425
47148
A219
D
S
W
R
L
W
P
A
G
D
K
S
Q
Q
K
Zebra Danio
Brachydanio rerio
NP_955831
425
47059
A219
D
S
W
R
L
W
P
A
G
D
R
S
Q
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9I7S8
429
47263
G224
S
W
R
L
W
P
A
G
D
K
R
L
M
V
D
Honey Bee
Apis mellifera
XP_624351
420
47251
G216
S
W
R
L
W
P
F
G
D
K
R
L
M
K
D
Nematode Worm
Caenorhab. elegans
Q10457
423
46959
E222
D
S
W
R
V
W
P
E
N
D
R
R
L
Q
L
Sea Urchin
Strong. purpuratus
XP_780342
419
46499
A213
D
S
W
R
L
W
P
A
G
D
K
R
L
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
N.A.
96.4
N.A.
95
96.2
N.A.
61.6
85.6
81.4
78.3
N.A.
58.7
54.5
49.6
62.1
Protein Similarity:
100
94
N.A.
98.3
N.A.
99.5
99
N.A.
69.6
92.4
90.3
91.7
N.A.
73.6
70.8
68.2
76
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
100
86.6
93.3
N.A.
6.6
6.6
60
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
6.6
13.3
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
0
8
0
0
0
0
0
16
77
0
0
0
0
16
% D
% Glu:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
70
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
16
16
0
0
8
62
% K
% Leu:
0
0
0
24
70
0
0
0
0
0
0
24
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
16
16
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
77
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
70
70
0
% Q
% Arg:
0
8
16
77
0
0
0
0
0
0
77
16
0
0
0
% R
% Ser:
16
77
0
0
0
0
0
47
0
0
0
62
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
16
% V
% Trp:
0
16
77
0
16
77
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _