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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GART All Species: 11.52
Human Site: S773 Identified Species: 23.03
UniProt: P22102 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22102 NP_000810.1 1010 107767 S773 V V A R A E G S P R V K V K N
Chimpanzee Pan troglodytes XP_514869 1010 107704 S773 V V A R A E G S P R V K V K N
Rhesus Macaque Macaca mulatta XP_001093303 909 97049 L698 P R V L P E K L G V D L D A Q
Dog Lupus familis XP_544864 745 79854 D537 A E P L F F L D Y F S C G K L
Cat Felis silvestris
Mouse Mus musculus Q64737 1010 107377 S773 V V A C P E D S P R V R V K N
Rat Rattus norvegicus NP_001011899 1010 107561 S773 V V E C P E D S P R V R V K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513896 1008 107242 P774 V T C P A G S P R V Q V D H L
Chicken Gallus gallus P21872 1003 106526 K769 G K V V P L Q K G S A H V K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571692 1017 107609 V778 P G A E S V V V R N L E R S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P00967 1353 144430 V1119 Y P Q R A A V V G E V V A R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785897 1012 107051 C774 I G Q V V P K C G D G A A V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07244 802 86050 G594 G E T S E M P G M Y P P G H Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 86.8 66.9 N.A. 85.6 86.5 N.A. 79.8 74.3 N.A. 66.8 N.A. 37.7 N.A. N.A. 58.9
Protein Similarity: 100 99.6 88.5 70.5 N.A. 93.7 93.8 N.A. 89.1 86.7 N.A. 81.3 N.A. 51.9 N.A. N.A. 73.5
P-Site Identity: 100 100 6.6 6.6 N.A. 73.3 66.6 N.A. 13.3 13.3 N.A. 6.6 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 100 6.6 6.6 N.A. 80 73.3 N.A. 13.3 13.3 N.A. 26.6 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 34 0 34 9 0 0 0 0 9 9 17 9 0 % A
% Cys: 0 0 9 17 0 0 0 9 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 9 0 9 9 0 17 0 0 % D
% Glu: 0 17 9 9 9 42 0 0 0 9 0 9 0 0 0 % E
% Phe: 0 0 0 0 9 9 0 0 0 9 0 0 0 0 0 % F
% Gly: 17 17 0 0 0 9 17 9 34 0 9 0 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 17 9 0 0 0 17 0 50 9 % K
% Leu: 0 0 0 17 0 9 9 9 0 0 9 9 0 0 25 % L
% Met: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 34 % N
% Pro: 17 9 9 9 34 9 9 9 34 0 9 9 0 0 0 % P
% Gln: 0 0 17 0 0 0 9 0 0 0 9 0 0 0 9 % Q
% Arg: 0 9 0 25 0 0 0 0 17 34 0 17 9 9 0 % R
% Ser: 0 0 0 9 9 0 9 34 0 9 9 0 0 9 9 % S
% Thr: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 42 34 17 17 9 9 17 17 0 17 42 17 42 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _