KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBL
All Species:
49.7
Human Site:
S178
Identified Species:
72.89
UniProt:
P22087
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22087
NP_001427.2
321
33784
S178
G
T
T
V
S
H
V
S
D
I
V
G
P
D
G
Chimpanzee
Pan troglodytes
XP_001135914
299
31246
V163
H
I
K
P
G
A
K
V
L
Y
L
G
A
A
S
Rhesus Macaque
Macaca mulatta
XP_001088664
401
42281
S257
G
T
T
V
S
H
V
S
D
I
V
G
P
D
G
Dog
Lupus familis
XP_533671
313
33300
S170
G
T
T
V
S
H
V
S
D
I
V
G
P
D
G
Cat
Felis silvestris
Mouse
Mus musculus
P35550
327
34288
S184
G
T
T
V
S
H
V
S
D
I
V
G
P
D
G
Rat
Rattus norvegicus
P22509
327
34203
S184
G
T
T
V
S
H
V
S
D
I
V
G
P
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517295
252
27451
G116
L
Y
L
G
A
A
S
G
T
T
V
S
H
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
P22232
323
34313
S180
G
T
T
V
S
H
V
S
D
V
V
G
P
E
G
Zebra Danio
Brachydanio rerio
NP_998167
317
33615
S174
G
T
T
V
S
H
V
S
D
I
V
G
P
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1V3
344
34618
S203
G
T
T
V
S
H
V
S
D
V
V
G
P
E
G
Honey Bee
Apis mellifera
XP_624378
310
32283
A167
G
T
T
V
S
H
V
A
D
V
V
G
P
E
G
Nematode Worm
Caenorhab. elegans
Q22053
352
36364
S209
G
T
T
V
S
H
C
S
D
V
V
G
P
E
G
Sea Urchin
Strong. purpuratus
XP_001175797
311
32878
S169
G
T
T
V
S
H
V
S
D
L
V
G
P
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FEF8
308
32811
S162
G
T
T
V
S
H
V
S
D
L
V
G
P
E
G
Baker's Yeast
Sacchar. cerevisiae
P15646
327
34447
S185
G
T
S
V
S
H
V
S
D
V
V
G
P
E
G
Red Bread Mold
Neurospora crassa
Q9HE26
323
33794
A180
G
T
S
V
S
H
V
A
D
I
V
G
P
T
G
Conservation
Percent
Protein Identity:
100
91.9
77.5
96.8
N.A.
96
95.4
N.A.
71
N.A.
82
81.3
N.A.
76.1
77.5
67.9
80
Protein Similarity:
100
92.2
78.5
96.8
N.A.
96
95.4
N.A.
74.7
N.A.
88.2
86.5
N.A.
81.9
84.1
76.4
85.6
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
N.A.
86.6
93.3
N.A.
86.6
80
80
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
13.3
N.A.
100
100
N.A.
100
100
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
71.3
66
66.5
Protein Similarity:
N.A.
N.A.
N.A.
78.8
76.4
76.7
P-Site Identity:
N.A.
N.A.
N.A.
86.6
80
80
P-Site Similarity:
N.A.
N.A.
N.A.
100
100
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
13
0
13
0
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
88
0
0
0
0
32
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
88
0
0
7
7
0
0
7
0
0
0
94
0
0
88
% G
% His:
7
0
0
0
0
88
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
44
0
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
7
0
0
0
0
0
7
13
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
88
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
88
0
7
75
0
0
0
7
0
0
13
% S
% Thr:
0
88
75
0
0
0
0
0
7
7
0
0
0
7
0
% T
% Val:
0
0
0
88
0
0
82
7
0
32
94
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _