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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP
All Species:
33.33
Human Site:
T486
Identified Species:
61.11
UniProt:
P22059
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22059
NP_002547.1
807
89421
T486
F
T
V
S
S
Y
S
T
T
V
F
R
T
S
K
Chimpanzee
Pan troglodytes
XP_508451
807
89429
T486
F
T
V
S
S
Y
S
T
T
V
F
R
T
S
K
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
T484
F
T
V
S
S
Y
S
T
T
V
F
R
T
S
K
Dog
Lupus familis
XP_540566
1109
121200
T788
F
T
V
S
S
Y
S
T
T
V
F
R
T
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3B7Z2
751
84671
T446
F
N
P
L
L
G
E
T
F
E
L
D
R
L
E
Rat
Rattus norvegicus
Q8K4M9
950
107747
S616
F
A
V
S
A
V
A
S
Q
W
E
R
T
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
S446
L
E
E
N
G
Y
R
S
L
C
E
Q
V
S
H
Chicken
Gallus gallus
XP_415293
788
88247
T466
F
S
V
S
S
Y
S
T
T
V
H
R
T
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139057
760
85799
L454
L
L
G
E
T
F
E
L
D
R
L
Q
E
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
T467
F
T
V
S
A
Y
A
T
T
T
N
R
T
G
K
Honey Bee
Apis mellifera
XP_392480
836
95642
T522
F
T
I
S
S
Y
S
T
T
A
S
R
T
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
F281
D
A
I
E
Q
F
Q
F
T
T
S
V
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
S867
F
T
A
S
M
Y
A
S
T
T
N
R
V
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
71.2
N.A.
90.5
29.4
N.A.
83.8
68.9
N.A.
68.4
N.A.
34.3
49.6
N.A.
42.8
Protein Similarity:
100
100
99.7
72.3
N.A.
91.9
42.8
N.A.
86.4
78.9
N.A.
78
N.A.
50.9
64
N.A.
52.9
P-Site Identity:
100
100
100
100
N.A.
13.3
40
N.A.
13.3
80
N.A.
6.6
N.A.
66.6
73.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
60
N.A.
33.3
93.3
N.A.
26.6
N.A.
80
80
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
16
0
24
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% D
% Glu:
0
8
8
16
0
0
16
0
0
8
16
0
8
0
8
% E
% Phe:
77
0
0
0
0
16
0
8
8
0
31
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
0
0
0
0
0
0
24
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% K
% Leu:
16
8
0
8
8
0
0
8
8
0
16
0
0
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
8
0
8
0
8
0
0
16
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
70
8
0
0
% R
% Ser:
0
8
0
70
47
0
47
24
0
0
16
0
0
54
0
% S
% Thr:
0
54
0
0
8
0
0
62
70
24
0
0
62
0
0
% T
% Val:
0
0
54
0
0
8
0
0
0
39
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _