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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP
All Species:
18.26
Human Site:
T4
Identified Species:
33.48
UniProt:
P22059
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22059
NP_002547.1
807
89421
T4
_
_
_
_
M
A
A
T
E
L
R
G
V
V
G
Chimpanzee
Pan troglodytes
XP_508451
807
89429
T4
_
_
_
_
M
A
A
T
E
L
R
G
V
V
G
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
T4
_
_
_
_
M
A
A
T
E
L
R
G
V
V
G
Dog
Lupus familis
XP_540566
1109
121200
T299
R
R
R
L
M
A
A
T
E
L
R
G
V
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3B7Z2
751
84671
T4
_
_
_
_
M
A
A
T
E
L
R
G
V
A
A
Rat
Rattus norvegicus
Q8K4M9
950
107747
E19
H
A
R
N
G
N
A
E
E
V
R
K
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
R5
_
_
_
M
R
R
F
R
A
L
Q
P
R
R
Q
Chicken
Gallus gallus
XP_415293
788
88247
G10
K
A
A
A
L
C
S
G
S
T
R
G
L
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139057
760
85799
P4
_
_
_
_
M
S
E
P
K
A
P
T
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
K12
A
G
N
A
L
A
E
K
G
L
P
E
M
K
G
Honey Bee
Apis mellifera
XP_392480
836
95642
L5
_
_
_
T
L
L
N
L
L
V
S
L
L
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
Y106
T
P
L
H
I
A
A
Y
Q
S
R
G
D
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
71.2
N.A.
90.5
29.4
N.A.
83.8
68.9
N.A.
68.4
N.A.
34.3
49.6
N.A.
42.8
Protein Similarity:
100
100
99.7
72.3
N.A.
91.9
42.8
N.A.
86.4
78.9
N.A.
78
N.A.
50.9
64
N.A.
52.9
P-Site Identity:
100
100
100
73.3
N.A.
81.8
20
N.A.
8.3
20
N.A.
9
N.A.
20
8.3
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
81.8
40
N.A.
16.6
40
N.A.
27.2
N.A.
40
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
16
0
54
54
0
8
8
0
0
0
16
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
16
8
47
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
0
0
8
8
0
0
54
0
0
39
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
8
8
0
0
8
0
8
0
% K
% Leu:
0
0
8
8
24
8
0
8
8
54
0
8
24
8
0
% L
% Met:
0
0
0
8
47
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
8
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
0
16
8
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% Q
% Arg:
8
8
16
0
8
8
0
8
0
0
62
0
8
8
0
% R
% Ser:
0
0
0
0
0
8
8
0
8
8
8
0
0
0
8
% S
% Thr:
8
0
0
8
0
0
0
39
0
8
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
16
0
0
39
47
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
54
54
54
39
0
0
0
0
0
0
0
0
0
0
0
% _