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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OSBP
All Species:
19.39
Human Site:
S345
Identified Species:
35.56
UniProt:
P22059
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22059
NP_002547.1
807
89421
S345
S
G
K
D
Q
C
C
S
G
K
G
D
M
S
D
Chimpanzee
Pan troglodytes
XP_508451
807
89429
S345
S
G
K
D
Q
C
C
S
G
K
G
D
M
S
D
Rhesus Macaque
Macaca mulatta
XP_001090190
805
89207
S343
S
G
K
D
Q
C
C
S
G
K
G
D
M
S
D
Dog
Lupus familis
XP_540566
1109
121200
S647
S
G
K
D
Q
C
C
S
G
K
G
D
M
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3B7Z2
751
84671
A306
D
E
N
E
F
F
D
A
P
E
I
I
T
M
P
Rat
Rattus norvegicus
Q8K4M9
950
107747
N430
T
K
Q
E
G
V
R
N
F
K
L
E
Q
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505999
738
84284
K306
V
P
E
S
L
G
H
K
R
T
G
S
N
I
S
Chicken
Gallus gallus
XP_415293
788
88247
S317
T
T
K
G
Q
C
L
S
A
K
G
E
A
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139057
760
85799
N314
Y
H
R
R
S
G
S
N
V
S
G
I
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477271
784
89306
S324
E
G
H
L
E
G
S
S
S
E
S
D
E
Q
K
Honey Bee
Apis mellifera
XP_392480
836
95642
E335
S
L
T
T
S
P
S
E
D
E
E
D
N
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790853
566
64483
T141
S
K
L
E
D
L
N
T
C
N
D
L
I
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35845
1188
135079
D711
A
T
K
E
S
D
E
D
S
D
A
D
E
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
71.2
N.A.
90.5
29.4
N.A.
83.8
68.9
N.A.
68.4
N.A.
34.3
49.6
N.A.
42.8
Protein Similarity:
100
100
99.7
72.3
N.A.
91.9
42.8
N.A.
86.4
78.9
N.A.
78
N.A.
50.9
64
N.A.
52.9
P-Site Identity:
100
100
100
100
N.A.
0
6.6
N.A.
6.6
53.3
N.A.
13.3
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
40
N.A.
13.3
66.6
N.A.
33.3
N.A.
33.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
8
0
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
39
31
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
31
8
8
8
8
8
8
8
54
0
0
39
% D
% Glu:
8
8
8
31
8
0
8
8
0
24
8
16
16
8
16
% E
% Phe:
0
0
0
0
8
8
0
0
8
0
0
0
0
8
8
% F
% Gly:
0
39
0
8
8
24
0
0
31
0
54
0
0
0
0
% G
% His:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
16
8
8
0
% I
% Lys:
0
16
47
0
0
0
0
8
0
47
0
0
0
0
16
% K
% Leu:
0
8
8
8
8
8
8
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
31
8
0
% M
% Asn:
0
0
8
0
0
0
8
16
0
8
0
0
16
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
39
0
0
0
0
0
0
0
8
8
8
% Q
% Arg:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
47
0
0
8
24
0
24
47
16
8
8
8
8
47
8
% S
% Thr:
16
16
8
8
0
0
0
8
0
8
0
0
8
0
0
% T
% Val:
8
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _