KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MUT
All Species:
27.58
Human Site:
S12
Identified Species:
60.67
UniProt:
P22033
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22033
NP_000246.2
750
83120
S12
K
N
Q
L
F
L
L
S
P
H
Y
L
R
Q
V
Chimpanzee
Pan troglodytes
XP_001146810
750
83144
S12
K
N
Q
L
F
L
L
S
P
H
Y
L
R
Q
V
Rhesus Macaque
Macaca mulatta
XP_001104455
750
83078
S12
K
N
Q
L
F
L
L
S
P
H
Y
L
K
Q
V
Dog
Lupus familis
XP_532164
903
99800
S165
K
T
R
L
L
L
L
S
P
H
H
L
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P16332
748
82947
S12
K
N
Q
L
F
L
L
S
P
H
Y
L
K
Q
L
Rat
Rattus norvegicus
XP_002727217
748
82907
S12
K
N
Q
L
F
L
L
S
P
H
Y
L
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510860
750
82679
S12
K
S
G
L
P
S
L
S
P
G
R
L
K
A
L
Chicken
Gallus gallus
XP_420055
748
82747
Q12
K
H
A
L
L
Y
L
Q
S
C
R
C
I
C
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092696
757
83499
S10
T
A
Q
K
A
C
I
S
L
T
A
R
R
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23381
744
81665
S20
C
S
T
R
P
S
S
S
G
A
Y
T
R
S
P
Sea Urchin
Strong. purpuratus
XP_781852
767
85131
K36
T
H
R
P
E
F
T
K
E
V
F
A
G
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
78.9
N.A.
92.5
95
N.A.
89.8
87.5
N.A.
80.7
N.A.
N.A.
N.A.
69.3
70.6
Protein Similarity:
100
100
99.5
81.5
N.A.
96.1
97.8
N.A.
95.5
94.5
N.A.
89.1
N.A.
N.A.
N.A.
81.7
83.7
P-Site Identity:
100
100
93.3
60
N.A.
86.6
86.6
N.A.
40
20
N.A.
20
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
60
26.6
N.A.
33.3
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
0
10
10
10
0
10
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
10
0
10
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
46
10
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
10
0
0
10
0
0
% G
% His:
0
19
0
0
0
0
0
0
0
55
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
73
0
0
10
0
0
0
10
0
0
0
0
46
0
0
% K
% Leu:
0
0
0
73
19
55
73
0
10
0
0
64
0
10
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
19
0
0
0
64
0
0
0
0
0
28
% P
% Gln:
0
0
55
0
0
0
0
10
0
0
0
0
0
55
0
% Q
% Arg:
0
0
19
10
0
0
0
0
0
0
19
10
37
0
0
% R
% Ser:
0
19
0
0
0
19
10
82
10
0
0
0
0
10
0
% S
% Thr:
19
10
10
0
0
0
10
0
0
10
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
55
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _