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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
23.94
Human Site:
T469
Identified Species:
47.88
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
T469
E
I
S
L
D
K
I
T
P
F
T
P
N
G
F
Chimpanzee
Pan troglodytes
XP_528711
477
53003
T469
E
I
S
L
D
K
I
T
P
F
T
P
N
G
F
Rhesus Macaque
Macaca mulatta
O77680
446
49274
T439
L
E
K
I
Q
P
I
T
Q
N
G
Q
H
P
T
Dog
Lupus familis
XP_545942
645
69818
T637
E
I
S
L
G
K
I
T
P
F
T
P
N
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
S467
E
V
S
L
G
K
I
S
P
L
T
P
N
C
F
Rat
Rattus norvegicus
P25115
475
52812
S464
E
V
S
L
G
K
I
S
P
L
T
P
N
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
G346
D
I
A
P
F
P
P
G
G
L
R
E
T
P
P
Chicken
Gallus gallus
XP_426351
648
69599
T640
E
I
S
L
G
K
I
T
P
F
T
P
N
G
L
Frog
Xenopus laevis
P42290
457
51638
T449
D
I
S
L
H
K
I
T
P
S
M
S
N
G
I
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
F456
S
L
D
T
I
T
P
F
T
S
T
G
L
M
E
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
G455
A
D
S
F
L
I
P
G
Q
I
Q
D
L
G
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
R451
H
R
L
A
Q
Y
K
R
L
G
S
E
H
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
13.3
86.6
N.A.
66.6
66.6
N.A.
6.6
86.6
60
6.6
13.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
86.6
N.A.
80
80
N.A.
20
86.6
66.6
13.3
13.3
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
17
9
9
0
17
0
0
0
0
0
0
9
0
0
9
% D
% Glu:
50
9
0
0
0
0
0
0
0
0
0
17
0
0
9
% E
% Phe:
0
0
0
9
9
0
0
9
0
34
0
0
0
0
34
% F
% Gly:
0
0
0
0
34
0
0
17
9
9
9
9
0
50
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
0
50
0
9
9
9
67
0
0
9
0
0
0
0
17
% I
% Lys:
0
0
9
0
0
59
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
9
59
9
0
0
0
9
25
0
0
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
59
0
9
% N
% Pro:
0
0
0
9
0
17
25
0
59
0
0
50
0
25
9
% P
% Gln:
0
0
0
0
17
0
0
0
17
0
9
9
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
9
0
0
0
0
% R
% Ser:
9
0
67
0
0
0
0
17
0
17
9
9
0
0
0
% S
% Thr:
0
0
0
9
0
9
0
50
9
0
59
0
9
0
9
% T
% Val:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _