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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
25.76
Human Site:
T386
Identified Species:
51.52
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
T386
C
S
R
T
P
V
E
T
V
N
I
S
N
E
L
Chimpanzee
Pan troglodytes
XP_528711
477
53003
T386
C
S
R
T
P
V
E
T
V
N
I
S
N
E
L
Rhesus Macaque
Macaca mulatta
O77680
446
49274
I363
N
A
I
E
T
V
S
I
N
N
N
G
A
A
M
Dog
Lupus familis
XP_545942
645
69818
T555
C
A
R
T
P
V
E
T
V
N
I
S
N
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
T381
C
F
R
T
P
V
Q
T
V
N
I
S
N
E
L
Rat
Rattus norvegicus
P25115
475
52812
T381
C
F
R
T
P
V
Q
T
V
N
I
S
N
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
R270
A
G
L
L
G
C
G
R
A
P
S
G
S
P
G
Chicken
Gallus gallus
XP_426351
648
69599
V564
Q
F
C
S
S
T
P
V
E
T
V
N
I
S
N
Frog
Xenopus laevis
P42290
457
51638
T372
C
S
T
T
P
V
E
T
V
N
I
S
N
E
L
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
T380
F
P
S
T
A
V
E
T
V
N
F
S
N
E
L
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
T376
V
S
Y
H
H
D
T
T
L
Q
K
E
P
V
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
E369
K
I
D
S
N
E
N
E
H
R
K
S
N
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
13.3
93.3
N.A.
86.6
86.6
N.A.
0
0
93.3
66.6
13.3
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
93.3
N.A.
6.6
20
93.3
66.6
20
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
9
0
0
0
9
0
0
0
9
9
0
% A
% Cys:
50
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
9
42
9
9
0
0
9
0
59
0
% E
% Phe:
9
25
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
0
9
0
9
0
0
0
0
17
0
0
9
% G
% His:
0
0
0
9
9
0
0
0
9
0
0
0
0
9
0
% H
% Ile:
0
9
9
0
0
0
0
9
0
0
50
0
9
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
9
0
0
0
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
0
9
0
9
0
9
67
9
9
67
0
9
% N
% Pro:
0
9
0
0
50
0
9
0
0
9
0
0
9
9
9
% P
% Gln:
9
0
0
0
0
0
17
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
42
0
0
0
0
9
0
9
0
0
0
0
0
% R
% Ser:
0
34
9
17
9
0
9
0
0
0
9
67
9
9
0
% S
% Thr:
0
0
9
59
9
9
9
67
0
9
0
0
0
0
0
% T
% Val:
9
0
0
0
0
67
0
9
59
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _