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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
31.52
Human Site:
T224
Identified Species:
63.03
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
T224
C
D
S
S
L
N
R
T
Y
A
I
S
S
S
L
Chimpanzee
Pan troglodytes
XP_528711
477
53003
T224
C
D
S
S
L
N
R
T
Y
A
I
S
S
S
L
Rhesus Macaque
Macaca mulatta
O77680
446
49274
V212
I
P
V
A
I
M
I
V
T
Y
T
R
I
Y
R
Dog
Lupus familis
XP_545942
645
69818
T393
C
D
S
S
L
N
R
T
Y
A
I
S
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
T218
C
D
S
S
L
N
R
T
Y
A
I
S
S
S
L
Rat
Rattus norvegicus
P25115
475
52812
T218
C
D
S
S
L
N
R
T
Y
A
I
S
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
R119
G
C
D
S
S
L
N
R
A
Y
A
V
S
S
S
Chicken
Gallus gallus
XP_426351
648
69599
T403
C
D
S
S
L
N
R
T
Y
A
I
S
S
S
L
Frog
Xenopus laevis
P42290
457
51638
S215
A
I
S
S
S
L
I
S
F
Y
I
P
V
A
I
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
T229
C
K
A
N
L
N
R
T
Y
A
I
S
S
S
L
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
G220
I
P
V
L
I
M
V
G
T
Y
T
R
I
F
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
Y214
C
V
F
L
L
N
P
Y
Y
A
V
I
S
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
20
100
20
80
0
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
20
100
46.6
93.3
6.6
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
9
67
9
0
0
9
0
% A
% Cys:
67
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
50
9
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
9
0
0
17
0
17
0
0
0
67
9
17
0
9
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
17
67
17
0
0
0
0
0
0
0
0
59
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
67
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
17
0
0
0
0
9
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
59
9
0
0
0
17
0
0
17
% R
% Ser:
0
0
59
67
17
0
0
9
0
0
0
59
75
75
9
% S
% Thr:
0
0
0
0
0
0
0
59
17
0
17
0
0
0
0
% T
% Val:
0
9
17
0
0
0
9
9
0
0
9
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
67
34
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _