KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
19.7
Human Site:
S283
Identified Species:
39.39
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
S283
A
A
C
A
P
D
T
S
L
R
A
S
I
K
K
Chimpanzee
Pan troglodytes
XP_528711
477
53003
S283
A
A
C
A
P
D
T
S
L
R
A
S
I
K
K
Rhesus Macaque
Macaca mulatta
O77680
446
49274
L271
F
K
R
E
T
K
V
L
K
T
L
S
V
I
M
Dog
Lupus familis
XP_545942
645
69818
S452
A
A
C
A
P
D
T
S
L
R
A
S
I
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
S277
G
A
C
E
P
D
P
S
L
R
A
S
I
K
K
Rat
Rattus norvegicus
P25115
475
52812
S277
G
A
Y
E
P
D
P
S
L
R
A
S
I
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
A178
A
G
P
P
D
R
P
A
R
S
G
P
R
A
S
Chicken
Gallus gallus
XP_426351
648
69599
T462
H
V
D
C
H
H
H
T
S
L
K
S
S
I
R
Frog
Xenopus laevis
P42290
457
51638
I274
Q
T
S
L
R
T
S
I
K
K
E
T
K
V
L
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
S288
N
D
C
S
N
E
N
S
L
K
T
T
F
K
K
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
I279
V
L
K
T
L
S
V
I
M
G
V
F
V
F
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
I273
A
A
K
T
L
G
T
I
L
G
V
F
I
C
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
6.6
100
N.A.
80
73.3
N.A.
6.6
6.6
0
33.3
0
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
13.3
100
N.A.
80
73.3
N.A.
13.3
20
20
60
13.3
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
50
0
25
0
0
0
9
0
0
42
0
0
9
0
% A
% Cys:
0
0
42
9
0
0
0
0
0
0
0
0
0
9
17
% C
% Asp:
0
9
9
0
9
42
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
25
0
9
0
0
0
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
17
9
9
0
% F
% Gly:
17
9
0
0
0
9
0
0
0
17
9
0
0
0
0
% G
% His:
9
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
25
0
0
0
0
50
17
0
% I
% Lys:
0
9
17
0
0
9
0
0
17
17
9
0
9
50
50
% K
% Leu:
0
9
0
9
17
0
0
9
59
9
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
9
42
0
25
0
0
0
0
9
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
9
9
0
0
9
42
0
0
9
0
9
% R
% Ser:
0
0
9
9
0
9
9
50
9
9
0
59
9
0
9
% S
% Thr:
0
9
0
17
9
9
34
9
0
9
9
17
0
0
0
% T
% Val:
9
9
0
0
0
0
17
0
0
0
17
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _