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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DRD5
All Species:
21.52
Human Site:
S219
Identified Species:
43.03
UniProt:
P21918
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21918
NP_000789.1
477
52951
S219
V
N
A
E
N
C
D
S
S
L
N
R
T
Y
A
Chimpanzee
Pan troglodytes
XP_528711
477
53003
S219
V
N
A
E
N
C
D
S
S
L
N
R
T
Y
A
Rhesus Macaque
Macaca mulatta
O77680
446
49274
V207
V
I
S
F
Y
I
P
V
A
I
M
I
V
T
Y
Dog
Lupus familis
XP_545942
645
69818
S388
A
R
A
E
N
C
D
S
S
L
N
R
T
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLD9
478
53058
S213
G
R
T
E
N
C
D
S
S
L
N
R
T
Y
A
Rat
Rattus norvegicus
P25115
475
52812
S213
G
R
T
E
N
C
D
S
S
L
N
R
T
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521446
353
37571
D114
R
P
A
S
T
G
C
D
S
S
L
N
R
A
Y
Chicken
Gallus gallus
XP_426351
648
69599
S398
G
P
S
E
S
C
D
S
S
L
N
R
T
Y
A
Frog
Xenopus laevis
P42290
457
51638
S210
L
N
R
T
Y
A
I
S
S
S
L
I
S
F
Y
Zebra Danio
Brachydanio rerio
XP_692025
474
53236
A224
D
Y
S
D
N
C
K
A
N
L
N
R
T
Y
A
Tiger Blowfish
Takifugu rubipres
P53454
463
51077
V215
L
I
S
F
Y
I
P
V
L
I
M
V
G
T
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198071
459
51464
F209
M
D
P
P
Q
C
V
F
L
L
N
P
Y
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
55.1
63.2
N.A.
82.8
82.3
N.A.
43.4
55.2
66.4
54.5
54.9
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
98.9
70.4
66.8
N.A.
88.9
87.8
N.A.
53.6
62.3
76.7
66.2
68.3
N.A.
N.A.
N.A.
51.3
P-Site Identity:
100
100
6.6
86.6
N.A.
80
80
N.A.
13.3
73.3
20
53.3
0
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
26.6
86.6
N.A.
80
80
N.A.
13.3
86.6
40
80
20
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
34
0
0
9
0
9
9
0
0
0
0
9
67
% A
% Cys:
0
0
0
0
0
67
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
9
0
0
50
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
17
0
0
0
9
0
0
0
0
0
9
0
% F
% Gly:
25
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
17
9
0
0
17
0
17
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
0
0
0
0
0
0
17
67
17
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% M
% Asn:
0
25
0
0
50
0
0
0
9
0
67
9
0
0
0
% N
% Pro:
0
17
9
9
0
0
17
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
25
9
0
0
0
0
0
0
0
0
59
9
0
0
% R
% Ser:
0
0
34
9
9
0
0
59
67
17
0
0
9
0
0
% S
% Thr:
0
0
17
9
9
0
0
0
0
0
0
0
59
17
0
% T
% Val:
25
0
0
0
0
0
9
17
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
25
0
0
0
0
0
0
0
9
67
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _