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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDHB
All Species:
27.27
Human Site:
S85
Identified Species:
50
UniProt:
P21912
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21912
NP_002991.2
280
31630
S85
K
I
K
N
E
V
D
S
T
L
T
F
R
R
S
Chimpanzee
Pan troglodytes
XP_001155328
281
31753
S86
K
I
K
N
E
V
D
S
T
L
T
F
R
R
S
Rhesus Macaque
Macaca mulatta
XP_001088349
280
31480
S85
K
I
K
N
E
I
D
S
T
L
T
F
R
R
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQA3
282
31795
S87
K
I
K
N
E
V
D
S
T
L
T
F
R
R
S
Rat
Rattus norvegicus
P21913
282
31811
S87
K
I
K
N
E
I
D
S
T
L
T
F
R
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YHT2
290
32578
S95
K
I
K
N
E
L
D
S
T
L
T
F
R
R
S
Frog
Xenopus laevis
Q3B8J8
282
31758
P87
K
I
K
N
E
V
D
P
T
L
T
F
R
R
S
Zebra Danio
Brachydanio rerio
A5PL98
280
31721
S84
K
I
K
N
E
M
D
S
T
L
T
F
R
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21914
297
33722
L94
K
N
E
M
D
P
T
L
T
F
R
R
S
C
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09545
298
32872
P99
K
I
K
N
E
V
D
P
T
L
T
F
R
R
S
Sea Urchin
Strong. purpuratus
XP_794003
281
31809
P85
K
I
K
N
E
L
D
P
T
L
T
F
R
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LB02
280
31122
N89
D
A
L
I
K
I
K
N
E
M
D
P
S
L
T
Baker's Yeast
Sacchar. cerevisiae
P21801
266
30213
Q77
L
L
K
I
K
D
E
Q
D
S
T
L
T
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.2
N.A.
N.A.
91.1
90.4
N.A.
N.A.
83.7
88.3
81
N.A.
65.6
N.A.
58.7
73.3
Protein Similarity:
100
99.6
98.9
N.A.
N.A.
93.9
93.6
N.A.
N.A.
90.3
91.4
86.4
N.A.
79.4
N.A.
73.4
84.7
P-Site Identity:
100
100
93.3
N.A.
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
13.3
N.A.
93.3
86.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
26.6
N.A.
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
56
65.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.1
76.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
8
8
77
0
8
0
8
0
0
0
0
% D
% Glu:
0
0
8
0
77
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
77
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
77
0
16
0
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
85
0
85
0
16
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
0
16
0
8
0
77
0
8
0
8
0
% L
% Met:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
77
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
24
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
8
77
77
16
% R
% Ser:
0
0
0
0
0
0
0
54
0
8
0
0
16
0
77
% S
% Thr:
0
0
0
0
0
0
8
0
85
0
85
0
8
0
8
% T
% Val:
0
0
0
0
0
39
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _