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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5E
All Species:
22.12
Human Site:
S549
Identified Species:
48.67
UniProt:
P21589
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21589
NP_002517.1
574
63368
S549
V
E
G
R
I
K
F
S
T
G
S
H
C
H
G
Chimpanzee
Pan troglodytes
XP_518619
590
65050
S566
D
E
L
L
R
H
D
S
G
D
Q
D
I
N
V
Rhesus Macaque
Macaca mulatta
XP_001086989
574
63244
S549
V
E
G
R
I
K
F
S
T
G
S
H
C
H
G
Dog
Lupus familis
XP_532221
538
58783
S513
V
E
G
R
I
K
F
S
A
G
S
R
C
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61503
576
63846
S551
V
E
G
R
I
K
F
S
A
A
S
H
Y
Q
G
Rat
Rattus norvegicus
P21588
576
63950
S551
V
E
G
R
I
K
F
S
A
A
S
H
Y
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513094
638
69373
S613
V
E
G
R
I
K
F
S
A
G
T
W
L
Q
G
Chicken
Gallus gallus
XP_419855
561
61905
V531
M
K
R
V
Y
P
A
V
E
G
R
I
K
F
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665677
572
63080
S548
V
E
G
R
I
Q
F
S
S
S
C
A
G
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611218
585
64394
I561
I
E
G
R
I
I
F
I
N
A
S
S
T
L
M
Honey Bee
Apis mellifera
XP_394018
593
65824
L559
I
E
W
R
I
T
Y
L
N
D
Q
I
M
H
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
98.6
76.1
N.A.
86.4
87.3
N.A.
67.7
62.3
N.A.
63.4
N.A.
38.9
40.1
N.A.
N.A.
Protein Similarity:
100
91.3
99.1
82.9
N.A.
93.9
93.5
N.A.
77.7
75.7
N.A.
79.9
N.A.
58.2
59.5
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
73.3
73.3
N.A.
66.6
6.6
N.A.
46.6
N.A.
40
26.6
N.A.
N.A.
P-Site Similarity:
100
20
100
86.6
N.A.
73.3
73.3
N.A.
73.3
20
N.A.
60
N.A.
46.6
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
37
28
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
28
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
19
0
10
0
0
0
% D
% Glu:
0
91
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
73
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
73
0
0
0
0
0
10
46
0
0
10
0
55
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
37
0
37
0
% H
% Ile:
19
0
0
0
82
10
0
10
0
0
0
19
10
0
0
% I
% Lys:
0
10
0
0
0
55
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
10
10
0
0
0
10
0
0
0
0
10
19
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
19
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
19
0
0
28
0
% Q
% Arg:
0
0
10
82
10
0
0
0
0
0
10
10
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
73
10
10
55
10
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
19
0
10
0
10
0
10
% T
% Val:
64
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _