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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP3
All Species:
16.06
Human Site:
Y443
Identified Species:
35.33
UniProt:
P21580
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21580
NP_006281.1
790
89614
Y443
G
A
S
R
G
E
A
Y
E
P
L
A
W
N
P
Chimpanzee
Pan troglodytes
XP_527515
976
109981
Y635
G
A
S
R
G
E
A
Y
E
P
L
A
W
N
P
Rhesus Macaque
Macaca mulatta
XP_001096105
790
89485
Y443
G
A
S
R
G
E
A
Y
E
P
L
A
W
N
P
Dog
Lupus familis
XP_541123
790
89438
Y443
G
P
S
R
G
E
A
Y
E
P
M
G
W
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60769
775
87577
L435
E
G
L
P
G
V
G
L
G
S
S
N
W
S
P
Rat
Rattus norvegicus
XP_001060914
814
91923
L473
G
G
L
P
A
V
G
L
G
S
S
N
W
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509168
792
89556
F445
A
A
S
R
T
E
A
F
E
S
L
G
W
A
P
Chicken
Gallus gallus
XP_423720
937
103557
S544
E
S
S
Q
G
D
L
S
V
P
G
E
K
S
C
Frog
Xenopus laevis
NP_001087109
781
89266
S440
E
Q
I
V
S
G
E
S
V
T
G
H
V
S
T
Zebra Danio
Brachydanio rerio
XP_692922
762
86249
P444
K
M
E
R
S
I
L
P
S
P
R
S
A
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795196
1187
131959
S720
D
T
D
I
P
E
F
S
R
R
F
S
T
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
98.2
90.2
N.A.
88.2
85.1
N.A.
76.8
22.6
55.8
48.4
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
80.1
98.8
95.1
N.A.
92.7
89.5
N.A.
85.2
38
69.4
64.6
N.A.
N.A.
N.A.
N.A.
37
P-Site Identity:
100
100
100
73.3
N.A.
20
26.6
N.A.
60
20
0
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
26.6
26.6
N.A.
66.6
46.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
37
0
0
10
0
46
0
0
0
0
28
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
28
0
10
0
0
55
10
0
46
0
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% F
% Gly:
46
19
0
0
55
10
19
0
19
0
19
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
19
0
0
0
19
19
0
0
37
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
19
0
37
0
% N
% Pro:
0
10
0
19
10
0
0
10
0
55
0
0
0
10
73
% P
% Gln:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
55
0
0
0
0
10
10
10
0
0
0
10
% R
% Ser:
0
10
55
0
19
0
0
28
10
28
19
19
0
37
0
% S
% Thr:
0
10
0
0
10
0
0
0
0
10
0
0
10
0
10
% T
% Val:
0
0
0
10
0
19
0
0
19
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% W
% Tyr:
0
0
0
0
0
0
0
37
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _