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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNFAIP3 All Species: 22.12
Human Site: Y345 Identified Species: 48.67
UniProt: P21580 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21580 NP_006281.1 790 89614 Y345 E I N L V D D Y F E L V Q H E
Chimpanzee Pan troglodytes XP_527515 976 109981 Y537 E I N L V D D Y F E L V Q H E
Rhesus Macaque Macaca mulatta XP_001096105 790 89485 Y345 E I N L V D D Y F E L V Q H E
Dog Lupus familis XP_541123 790 89438 Y345 E I N L V D D Y F E L V Q H E
Cat Felis silvestris
Mouse Mus musculus Q60769 775 87577 E338 D E A N L P K E I N L V D D Y
Rat Rattus norvegicus XP_001060914 814 91923 E375 D E A N L P K E I N L V D D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509168 792 89556 Y346 E I N L V D D Y F E L V Q H E
Chicken Gallus gallus XP_423720 937 103557 C444 E S D K E S V C S S S A S N G
Frog Xenopus laevis NP_001087109 781 89266 V343 L P K E L H L V D D F V E L V
Zebra Danio Brachydanio rerio XP_692922 762 86249 Y347 D M N L M E D Y L Q L V N H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795196 1187 131959 F601 D T N V V N E F R V G S K Q C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80 98.2 90.2 N.A. 88.2 85.1 N.A. 76.8 22.6 55.8 48.4 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 80.1 98.8 95.1 N.A. 92.7 89.5 N.A. 85.2 38 69.4 64.6 N.A. N.A. N.A. N.A. 37
P-Site Identity: 100 100 100 100 N.A. 13.3 13.3 N.A. 100 6.6 6.6 53.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 26.6 26.6 N.A. 100 20 26.6 86.6 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % C
% Asp: 37 0 10 0 0 46 55 0 10 10 0 0 19 19 0 % D
% Glu: 55 19 0 10 10 10 10 19 0 46 0 0 10 0 55 % E
% Phe: 0 0 0 0 0 0 0 10 46 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 55 0 % H
% Ile: 0 46 0 0 0 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 0 0 10 10 0 0 19 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 0 55 28 0 10 0 10 0 73 0 0 10 0 % L
% Met: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 64 19 0 10 0 0 0 19 0 0 10 10 0 % N
% Pro: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 46 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 10 0 0 10 10 10 10 10 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 55 0 10 10 0 10 0 82 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 0 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _