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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP3
All Species:
27.88
Human Site:
S605
Identified Species:
61.33
UniProt:
P21580
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21580
NP_006281.1
790
89614
S605
P
G
D
R
T
G
T
S
K
C
R
K
A
G
C
Chimpanzee
Pan troglodytes
XP_527515
976
109981
S797
P
G
D
R
T
G
T
S
K
C
R
K
A
G
C
Rhesus Macaque
Macaca mulatta
XP_001096105
790
89485
S605
P
G
D
R
T
G
T
S
K
C
R
K
A
G
C
Dog
Lupus familis
XP_541123
790
89438
S605
P
G
D
R
T
G
T
S
K
C
R
K
A
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60769
775
87577
S590
P
G
D
R
A
G
T
S
K
C
R
K
A
G
C
Rat
Rattus norvegicus
XP_001060914
814
91923
S629
P
A
D
R
T
G
T
S
K
C
R
K
A
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509168
792
89556
S606
P
E
D
R
K
G
T
S
K
C
R
K
A
G
C
Chicken
Gallus gallus
XP_423720
937
103557
Q742
Q
R
G
R
G
G
V
Q
Q
P
R
T
Q
T
Y
Frog
Xenopus laevis
NP_001087109
781
89266
T595
E
N
R
K
C
R
K
T
G
C
P
F
F
G
T
Zebra Danio
Brachydanio rerio
XP_692922
762
86249
T606
I
C
Y
L
D
Y
Q
T
N
H
Q
A
T
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795196
1187
131959
K929
R
C
L
D
F
V
D
K
V
N
Q
V
E
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
98.2
90.2
N.A.
88.2
85.1
N.A.
76.8
22.6
55.8
48.4
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
80.1
98.8
95.1
N.A.
92.7
89.5
N.A.
85.2
38
69.4
64.6
N.A.
N.A.
N.A.
N.A.
37
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
20
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
26.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
0
0
10
64
10
19
% A
% Cys:
0
19
0
0
10
0
0
0
0
73
0
0
0
0
64
% C
% Asp:
0
0
64
10
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
0
46
10
0
10
73
0
0
10
0
0
0
0
73
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
10
64
0
0
64
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
64
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% P
% Gln:
10
0
0
0
0
0
10
10
10
0
19
0
10
0
0
% Q
% Arg:
10
10
10
73
0
10
0
0
0
0
73
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
46
0
64
19
0
0
0
10
10
10
10
% T
% Val:
0
0
0
0
0
10
10
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _