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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP3
All Species:
16.97
Human Site:
S423
Identified Species:
37.33
UniProt:
P21580
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21580
NP_006281.1
790
89614
S423
N
K
L
P
K
L
N
S
K
P
G
P
E
G
L
Chimpanzee
Pan troglodytes
XP_527515
976
109981
S615
N
K
L
P
K
L
N
S
K
P
G
P
E
G
L
Rhesus Macaque
Macaca mulatta
XP_001096105
790
89485
S423
N
K
L
P
K
L
N
S
K
P
G
P
E
G
L
Dog
Lupus familis
XP_541123
790
89438
S423
S
K
S
S
R
L
H
S
K
P
G
P
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60769
775
87577
Q415
S
E
R
R
Q
K
N
Q
S
K
L
P
K
L
N
Rat
Rattus norvegicus
XP_001060914
814
91923
S453
E
R
R
Q
K
N
Q
S
K
L
P
K
L
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509168
792
89556
S425
N
K
S
R
K
P
N
S
K
A
G
A
E
K
L
Chicken
Gallus gallus
XP_423720
937
103557
K524
G
D
T
L
E
K
K
K
K
G
S
L
K
T
R
Frog
Xenopus laevis
NP_001087109
781
89266
E420
N
R
Q
K
Q
K
S
E
S
V
E
H
S
S
E
Zebra Danio
Brachydanio rerio
XP_692922
762
86249
I424
K
P
E
A
I
S
T
I
N
Q
T
S
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795196
1187
131959
S700
I
G
K
A
A
G
L
S
L
K
T
M
G
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
98.2
90.2
N.A.
88.2
85.1
N.A.
76.8
22.6
55.8
48.4
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
80.1
98.8
95.1
N.A.
92.7
89.5
N.A.
85.2
38
69.4
64.6
N.A.
N.A.
N.A.
N.A.
37
P-Site Identity:
100
100
100
60
N.A.
13.3
20
N.A.
60
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
40
26.6
N.A.
60
20
26.6
0
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
10
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
10
10
0
10
0
0
10
0
0
10
0
46
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
10
0
0
0
10
46
0
10
28
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
46
10
10
46
28
10
10
64
19
0
10
19
10
10
% K
% Leu:
0
0
28
10
0
37
10
0
10
10
10
10
10
10
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
46
0
0
0
0
10
46
0
10
0
0
0
0
10
10
% N
% Pro:
0
10
0
28
0
10
0
0
0
37
10
46
0
0
0
% P
% Gln:
0
0
10
10
19
0
10
10
0
10
0
0
0
0
0
% Q
% Arg:
0
19
19
19
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
19
0
19
10
0
10
10
64
19
0
10
10
19
19
10
% S
% Thr:
0
0
10
0
0
0
10
0
0
0
19
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _