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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFAIP3
All Species:
26.97
Human Site:
S146
Identified Species:
59.33
UniProt:
P21580
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21580
NP_006281.1
790
89614
S146
K
F
R
W
Q
L
E
S
L
K
S
Q
E
F
V
Chimpanzee
Pan troglodytes
XP_527515
976
109981
S338
K
F
R
W
Q
L
E
S
L
K
S
Q
E
F
V
Rhesus Macaque
Macaca mulatta
XP_001096105
790
89485
S146
K
F
R
W
Q
L
E
S
L
K
S
Q
E
F
V
Dog
Lupus familis
XP_541123
790
89438
S146
K
F
R
W
Q
L
E
S
L
K
S
Q
E
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60769
775
87577
S146
K
F
R
W
Q
L
E
S
L
K
S
Q
E
F
V
Rat
Rattus norvegicus
XP_001060914
814
91923
S183
K
F
R
W
Q
L
E
S
L
K
S
Q
E
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509168
792
89556
S147
K
F
R
W
Q
N
E
S
I
K
S
Q
E
F
V
Chicken
Gallus gallus
XP_423720
937
103557
Q208
L
K
R
R
W
R
W
Q
Q
T
Q
Q
N
K
E
Frog
Xenopus laevis
NP_001087109
781
89266
C147
K
F
R
W
Q
L
E
C
V
K
S
M
E
F
T
Zebra Danio
Brachydanio rerio
XP_692922
762
86249
L150
L
T
R
F
Q
T
E
L
L
H
S
Q
E
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795196
1187
131959
R162
E
R
R
W
R
R
E
R
N
Q
F
D
T
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
98.2
90.2
N.A.
88.2
85.1
N.A.
76.8
22.6
55.8
48.4
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
80.1
98.8
95.1
N.A.
92.7
89.5
N.A.
85.2
38
69.4
64.6
N.A.
N.A.
N.A.
N.A.
37
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
13.3
73.3
53.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
13.3
80
60
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
0
0
0
91
0
0
0
0
0
82
0
10
% E
% Phe:
0
73
0
10
0
0
0
0
0
0
10
0
0
82
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
73
10
0
0
0
0
0
0
0
73
0
0
0
10
0
% K
% Leu:
19
0
0
0
0
64
0
10
64
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
82
0
0
10
10
10
10
82
0
0
0
% Q
% Arg:
0
10
100
10
10
19
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
82
0
0
0
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
10
0
0
10
10
19
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
64
% V
% Trp:
0
0
0
82
10
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _