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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT
All Species:
30.61
Human Site:
Y260
Identified Species:
56.11
UniProt:
P21549
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21549
NP_000021.1
392
43010
Y260
C
D
D
Q
P
R
M
Y
H
H
T
I
P
V
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090301
392
43169
Y260
C
D
G
Q
P
R
M
Y
H
H
T
I
P
V
I
Dog
Lupus familis
XP_848328
413
44678
Y282
C
D
D
Q
P
R
V
Y
H
H
T
T
P
V
I
Cat
Felis silvestris
Mouse
Mus musculus
O35423
413
45797
I282
C
E
G
E
T
R
V
I
H
H
T
T
P
V
T
Rat
Rattus norvegicus
P09139
414
45816
I282
C
E
G
K
T
R
V
I
H
H
T
L
P
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513675
392
43071
Y260
C
D
D
K
P
R
I
Y
H
H
T
T
P
V
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081948
415
44968
Y283
C
D
G
K
P
R
I
Y
H
H
T
G
P
V
T
Zebra Danio
Brachydanio rerio
NP_001002331
391
42601
Y259
D
D
K
P
V
R
S
Y
H
H
T
G
P
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511062
394
43781
Y256
C
Y
G
T
P
R
I
Y
H
H
T
I
S
S
T
Honey Bee
Apis mellifera
XP_397119
397
44245
Y265
F
G
N
E
D
R
V
Y
H
H
T
M
S
A
T
Nematode Worm
Caenorhab. elegans
NP_495885
405
43935
Y277
C
D
G
E
L
K
R
Y
H
H
T
A
P
I
S
Sea Urchin
Strong. purpuratus
XP_780986
394
42901
Y261
C
D
A
G
P
R
R
Y
H
H
T
C
P
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YA5
401
44190
T250
L
G
T
Y
W
P
Y
T
P
S
I
Q
L
L
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.3
75.5
N.A.
72.4
75.3
N.A.
73.2
N.A.
62.6
58.6
N.A.
44.6
46.3
41.4
54.5
Protein Similarity:
100
N.A.
95.9
82.3
N.A.
81.3
83.5
N.A.
86.2
N.A.
77.8
77
N.A.
61.4
64.2
61.9
72.8
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
46.6
53.3
N.A.
80
N.A.
66.6
53.3
N.A.
53.3
33.3
46.6
66.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
66.6
80
N.A.
93.3
N.A.
80
53.3
N.A.
60
60
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% A
% Cys:
77
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
62
24
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
0
24
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
47
8
0
0
0
0
0
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
93
93
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
24
16
0
0
8
24
0
8
39
% I
% Lys:
0
0
8
24
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
0
0
0
0
0
0
8
8
8
0
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
54
8
0
0
8
0
0
0
77
0
0
% P
% Gln:
0
0
0
24
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
85
16
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
8
0
0
16
8
16
% S
% Thr:
0
0
8
8
16
0
0
8
0
0
93
24
0
0
39
% T
% Val:
0
0
0
0
8
0
31
0
0
0
0
0
0
70
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
8
77
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _