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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT
All Species:
35.15
Human Site:
T235
Identified Species:
64.44
UniProt:
P21549
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21549
NP_000021.1
392
43010
T235
K
K
M
Y
S
R
K
T
K
P
F
S
F
Y
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090301
392
43169
T235
K
K
M
Y
S
R
K
T
K
P
F
S
F
Y
L
Dog
Lupus familis
XP_848328
413
44678
T257
S
K
I
Y
A
R
K
T
K
P
V
S
F
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
O35423
413
45797
T257
Y
K
V
Y
S
R
K
T
K
P
V
S
F
Y
T
Rat
Rattus norvegicus
P09139
414
45816
T257
S
K
V
Y
S
R
K
T
K
P
V
S
F
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513675
392
43071
T235
K
K
I
F
S
R
K
T
K
P
V
S
F
A
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081948
415
44968
T258
K
K
M
F
G
R
K
T
K
P
P
S
L
Y
V
Zebra Danio
Brachydanio rerio
NP_001002331
391
42601
T233
H
K
I
F
N
R
K
T
K
P
I
S
Y
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511062
394
43781
T231
T
R
I
R
K
R
K
T
K
P
K
V
Y
Y
F
Honey Bee
Apis mellifera
XP_397119
397
44245
T239
K
K
L
F
E
R
K
T
K
P
S
S
F
Y
W
Nematode Worm
Caenorhab. elegans
NP_495885
405
43935
Q252
E
K
I
R
N
R
K
Q
R
V
A
S
F
Y
F
Sea Urchin
Strong. purpuratus
XP_780986
394
42901
I236
S
K
F
K
S
K
K
I
R
V
P
S
F
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YA5
401
44190
S227
E
A
T
K
T
S
K
S
L
K
V
F
F
D
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.3
75.5
N.A.
72.4
75.3
N.A.
73.2
N.A.
62.6
58.6
N.A.
44.6
46.3
41.4
54.5
Protein Similarity:
100
N.A.
95.9
82.3
N.A.
81.3
83.5
N.A.
86.2
N.A.
77.8
77
N.A.
61.4
64.2
61.9
72.8
P-Site Identity:
100
N.A.
100
73.3
N.A.
73.3
73.3
N.A.
73.3
N.A.
66.6
53.3
N.A.
40
66.6
40
46.6
P-Site Similarity:
100
N.A.
100
86.6
N.A.
80
80
N.A.
86.6
N.A.
80
86.6
N.A.
60
80
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
16
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
31
0
0
0
0
0
0
16
8
77
8
16
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
39
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
39
85
0
16
8
8
100
0
77
8
8
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
47
% L
% Met:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
77
16
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
16
0
85
0
0
16
0
0
0
0
0
0
% R
% Ser:
24
0
0
0
47
8
0
8
0
0
8
85
0
0
0
% S
% Thr:
8
0
8
0
8
0
0
77
0
0
0
0
0
0
16
% T
% Val:
0
0
16
0
0
0
0
0
0
16
39
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% W
% Tyr:
8
0
0
39
0
0
0
0
0
0
0
0
16
77
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _