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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT
All Species:
8.48
Human Site:
T127
Identified Species:
15.56
UniProt:
P21549
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21549
NP_000021.1
392
43010
T127
G
A
R
V
H
P
M
T
K
D
P
G
G
H
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090301
392
43169
T127
G
A
R
V
H
P
M
T
K
D
P
G
G
H
Y
Dog
Lupus familis
XP_848328
413
44678
V149
G
A
R
V
H
S
M
V
K
D
P
G
D
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35423
413
45797
I149
G
A
R
V
H
Q
M
I
K
K
P
G
E
H
Y
Rat
Rattus norvegicus
P09139
414
45816
I149
G
A
R
V
H
Q
M
I
K
K
P
G
E
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513675
392
43071
V127
G
G
K
V
H
Q
L
V
K
S
P
G
G
Y
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081948
415
44968
S150
G
A
D
V
R
Y
V
S
K
P
V
G
E
A
F
Zebra Danio
Brachydanio rerio
NP_001002331
391
42601
E125
G
A
K
V
N
T
V
E
T
M
A
G
G
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511062
394
43781
E122
G
A
E
V
H
Y
V
E
A
S
F
G
R
A
L
Honey Bee
Apis mellifera
XP_397119
397
44245
E131
G
A
N
V
K
L
L
E
T
D
Y
T
K
G
I
Nematode Worm
Caenorhab. elegans
NP_495885
405
43935
T144
G
I
E
V
K
K
I
T
A
P
Q
G
Q
A
V
Sea Urchin
Strong. purpuratus
XP_780986
394
42901
Q128
G
A
N
V
K
V
L
Q
N
P
T
G
V
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YA5
401
44190
E114
N
F
N
V
D
V
V
E
S
D
W
G
Q
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.3
75.5
N.A.
72.4
75.3
N.A.
73.2
N.A.
62.6
58.6
N.A.
44.6
46.3
41.4
54.5
Protein Similarity:
100
N.A.
95.9
82.3
N.A.
81.3
83.5
N.A.
86.2
N.A.
77.8
77
N.A.
61.4
64.2
61.9
72.8
P-Site Identity:
100
N.A.
100
73.3
N.A.
73.3
73.3
N.A.
53.3
N.A.
33.3
33.3
N.A.
33.3
26.6
26.6
26.6
P-Site Similarity:
100
N.A.
100
80
N.A.
73.3
73.3
N.A.
73.3
N.A.
53.3
60
N.A.
40
33.3
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
0
0
0
0
0
16
0
8
0
0
31
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
39
0
0
8
0
0
% D
% Glu:
0
0
16
0
0
0
0
31
0
0
0
0
24
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
16
% F
% Gly:
93
8
0
0
0
0
0
0
0
0
0
93
31
16
0
% G
% His:
0
0
0
0
54
0
0
0
0
0
0
0
0
31
0
% H
% Ile:
0
8
0
0
0
0
8
16
0
0
0
0
0
0
8
% I
% Lys:
0
0
16
0
24
8
0
0
54
16
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
8
24
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
39
0
0
8
0
0
0
0
0
% M
% Asn:
8
0
24
0
8
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
24
47
0
0
0
0
% P
% Gln:
0
0
0
0
0
24
0
8
0
0
8
0
16
0
0
% Q
% Arg:
0
0
39
0
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
8
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
24
16
0
8
8
0
0
0
% T
% Val:
0
0
0
100
0
16
31
16
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
0
0
0
8
0
0
24
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _