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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT
All Species:
41.52
Human Site:
S221
Identified Species:
76.11
UniProt:
P21549
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21549
NP_000021.1
392
43010
S221
P
P
G
T
S
L
I
S
F
S
D
K
A
K
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090301
392
43169
S221
P
P
G
T
S
F
I
S
F
S
D
K
A
K
K
Dog
Lupus familis
XP_848328
413
44678
S243
P
P
G
T
S
L
I
S
F
S
D
K
A
K
S
Cat
Felis silvestris
Mouse
Mus musculus
O35423
413
45797
S243
P
P
G
I
S
L
I
S
F
N
D
K
A
K
Y
Rat
Rattus norvegicus
P09139
414
45816
S243
P
P
G
I
S
L
I
S
F
N
D
K
A
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513675
392
43071
S221
P
P
G
T
S
I
I
S
F
S
E
K
A
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081948
415
44968
S244
P
P
G
T
A
P
I
S
F
S
E
A
A
S
K
Zebra Danio
Brachydanio rerio
NP_001002331
391
42601
S219
P
P
G
T
A
P
I
S
F
S
E
R
A
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511062
394
43781
S217
P
A
G
L
T
P
I
S
F
S
K
R
A
L
T
Honey Bee
Apis mellifera
XP_397119
397
44245
S225
P
P
G
L
A
P
I
S
F
S
P
R
A
E
K
Nematode Worm
Caenorhab. elegans
NP_495885
405
43935
S238
P
P
G
L
A
P
I
S
F
S
D
R
A
M
E
Sea Urchin
Strong. purpuratus
XP_780986
394
42901
S222
P
P
G
T
A
P
I
S
F
S
Q
R
A
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YA5
401
44190
C213
P
T
G
L
G
I
V
C
A
S
P
K
A
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.3
75.5
N.A.
72.4
75.3
N.A.
73.2
N.A.
62.6
58.6
N.A.
44.6
46.3
41.4
54.5
Protein Similarity:
100
N.A.
95.9
82.3
N.A.
81.3
83.5
N.A.
86.2
N.A.
77.8
77
N.A.
61.4
64.2
61.9
72.8
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
80
80
N.A.
80
N.A.
66.6
60
N.A.
46.6
60
60
60
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
100
N.A.
80
80
N.A.
60
80
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
39
0
0
0
8
0
0
8
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
24
0
0
8
16
% E
% Phe:
0
0
0
0
0
8
0
0
93
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
16
0
16
93
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
54
0
39
39
% K
% Leu:
0
0
0
31
0
31
0
0
0
0
0
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% N
% Pro:
100
85
0
0
0
47
0
0
0
0
16
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
39
0
8
0
% R
% Ser:
0
0
0
0
47
0
0
93
0
85
0
0
0
8
24
% S
% Thr:
0
8
0
54
8
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _