KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPDH1
All Species:
47.58
Human Site:
T306
Identified Species:
87.22
UniProt:
P20839
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20839
NP_001096075.1
514
55406
T306
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Chimpanzee
Pan troglodytes
XP_516452
608
66107
T376
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Rhesus Macaque
Macaca mulatta
XP_001089341
530
57059
T322
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Dog
Lupus familis
XP_850999
611
65030
T403
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P50096
514
55276
T306
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Rat
Rattus norvegicus
NP_001102089
548
58591
T340
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509219
535
57111
Q336
Y
I
K
Q
K
Y
P
Q
L
Q
V
I
G
G
N
Chicken
Gallus gallus
NP_001025772
514
55540
T306
V
I
G
G
N
V
V
T
A
A
Q
A
K
N
L
Frog
Xenopus laevis
NP_001080792
514
55674
T306
V
V
G
G
N
V
V
T
A
A
Q
A
K
N
L
Zebra Danio
Brachydanio rerio
NP_001014391
514
55622
T306
V
V
G
G
N
V
V
T
A
A
Q
A
K
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07152
537
57811
T325
V
I
G
G
N
V
V
T
R
A
Q
A
K
N
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SA34
502
54033
T296
V
V
G
G
N
V
V
T
M
Y
Q
A
E
N
L
Baker's Yeast
Sacchar. cerevisiae
P50094
524
56375
T311
I
I
A
G
N
V
A
T
R
E
Q
A
A
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.2
92.4
80.6
N.A.
97.2
87.9
N.A.
85.2
83.6
92
90.6
N.A.
66.1
N.A.
N.A.
N.A.
Protein Similarity:
100
77.6
92.8
82
N.A.
98.8
88.8
N.A.
87
92
96.5
96.3
N.A.
80.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.6
61.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.7
77.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
70
77
0
93
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
85
93
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
77
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
0
0
0
0
77
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
93
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
93
0
0
0
0
0
0
0
0
93
8
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
8
93
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% T
% Val:
85
24
0
0
0
93
85
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _