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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPDH1
All Species:
30.61
Human Site:
T19
Identified Species:
56.11
UniProt:
P20839
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20839
NP_001096075.1
514
55406
T19
Y
V
P
E
D
G
L
T
A
Q
Q
L
F
A
S
Chimpanzee
Pan troglodytes
XP_516452
608
66107
T89
Y
V
P
D
D
G
L
T
A
Q
Q
L
F
N
C
Rhesus Macaque
Macaca mulatta
XP_001089341
530
57059
Y36
H
E
T
A
A
Q
R
Y
S
A
R
L
L
Q
A
Dog
Lupus familis
XP_850999
611
65030
V116
H
L
R
P
A
A
L
V
A
P
Q
V
H
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P50096
514
55276
T19
Y
V
P
E
D
G
L
T
A
H
E
L
F
A
N
Rat
Rattus norvegicus
NP_001102089
548
58591
A23
P
L
L
Q
G
G
G
A
A
A
A
P
E
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509219
535
57111
T59
Y
V
P
L
D
G
L
T
A
Q
Q
L
F
A
I
Chicken
Gallus gallus
NP_001025772
514
55540
T19
Y
V
P
D
D
G
L
T
A
Q
Q
L
F
S
C
Frog
Xenopus laevis
NP_001080792
514
55674
T19
Y
V
P
E
D
G
L
T
A
Q
Q
L
F
A
N
Zebra Danio
Brachydanio rerio
NP_001014391
514
55622
S19
Y
I
P
D
D
G
L
S
A
Q
Q
L
F
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07152
537
57811
S41
A
E
L
Q
D
G
L
S
C
K
E
L
F
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SA34
502
54033
S19
K
L
F
S
Q
G
Y
S
Y
T
Y
D
D
V
I
Baker's Yeast
Sacchar. cerevisiae
P50094
524
56375
Q27
S
K
D
G
L
S
V
Q
E
L
M
D
S
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.2
92.4
80.6
N.A.
97.2
87.9
N.A.
85.2
83.6
92
90.6
N.A.
66.1
N.A.
N.A.
N.A.
Protein Similarity:
100
77.6
92.8
82
N.A.
98.8
88.8
N.A.
87
92
96.5
96.3
N.A.
80.4
N.A.
N.A.
N.A.
P-Site Identity:
100
80
6.6
20
N.A.
80
13.3
N.A.
86.6
80
93.3
73.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
33.3
40
N.A.
93.3
26.6
N.A.
86.6
93.3
100
93.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.6
61.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.7
77.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
16
8
0
8
70
16
8
0
0
39
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
16
% C
% Asp:
0
0
8
24
62
0
0
0
0
0
0
16
8
0
0
% D
% Glu:
0
16
0
24
0
0
0
0
8
0
16
0
8
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
62
0
0
% F
% Gly:
0
0
0
8
8
77
8
0
0
0
0
0
0
0
8
% G
% His:
16
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
24
16
8
8
0
70
0
0
8
0
70
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
24
% N
% Pro:
8
0
54
8
0
0
0
0
0
8
0
8
0
8
8
% P
% Gln:
0
0
0
16
8
8
0
8
0
47
54
0
0
16
0
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
8
0
0
8
0
% R
% Ser:
8
0
0
8
0
8
0
24
8
0
0
0
8
8
8
% S
% Thr:
0
0
8
0
0
0
0
47
0
8
0
0
0
8
8
% T
% Val:
0
47
0
0
0
0
8
8
0
0
0
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
0
0
8
8
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _